Epidemiology of herpesvirus papio infection in a large captive baboon colony: similarities to Epstein-Barr virus infection in humans.
J Infect Dis
; 181(4): 1462-6, 2000 Apr.
Article
en En
| MEDLINE
| ID: mdl-10762578
The epidemiology of herpesvirus papio, a lymphocryptovirus similar to Epstein-Barr virus (EBV), was studied in a captive colony of >1900 baboons. Herpesvirus papio IgG antibody titers were measured by IFA. In total, 438 specimens from 296 baboons were assessed, including 116 serial specimens from 52 juveniles and 6 infants studied monthly for 1 year following birth and at age 18 months. Maternally derived antibody reached a nadir at 4 months of age. About 75% of animals at 12 months of age and >95% of animals after age 24 months demonstrated serologic evidence of herpesvirus papio infection. After age 3 years, the geometric mean titer was 1:60-75. The epidemiology of herpesvirus papio infection in baboons closely parallels that of EBV infection in humans. An animal model of lymphocryptovirus infection will facilitate investigations of human lymphocryptovirus biology.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Herpesviridae
/
Infecciones por Virus de Epstein-Barr
/
Enfermedades de los Monos
Tipo de estudio:
Screening_studies
Límite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Infect Dis
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos