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Symptomatic vertebral hemangiomas: treatment by means of direct intralesional injection of ethanol.
Doppman, J L; Oldfield, E H; Heiss, J D.
Afiliación
  • Doppman JL; Department of Diagnostic Radiology, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bldg 10, Rm 1C660, Bethesda, MD 20892-1182, USA. jdoppman@nih.gov
Radiology ; 214(2): 341-8, 2000 Feb.
Article en En | MEDLINE | ID: mdl-10671579
PURPOSE: To describe the technique and results of injecting ethanol directly into symptomatic vertebral hemangiomas. MATERIALS AND METHODS: Eleven patients with paraplegia (n = 6) or radiculopathy (n = 5) due to vertebral hemangioma were treated by means of injecting ethanol (5-50 mL) directly into the lesion with computed tomographic (CT) guidance. CT angiograms were essential prior to treatment to identify functional vascular spaces of the hemangioma and direct needle placement. RESULTS: All hemangiomas were obliterated completely at follow-up angiography and gadolinium-enhanced magnetic resonance imaging. Five of six patients with paraplegia recovered completely: One who was treated recently was walking with assistance. Four of five patients with radiculopathy improved. No immediate complications were associated with ethanol injection. The two patients who received the largest volumes of ethanol, 42 and 50 mL, developed pathologic fractures of the involved vertebrae 4 and 16 weeks after treatment. CONCLUSION: Direct injection of ethanol into symptomatic vertebral hemangioma is an effective and safe treatment, provided the dose is less than 15 mL.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Soluciones Esclerosantes / Neoplasias de la Columna Vertebral / Vértebras Torácicas / Etanol / Hemangioma / Vértebras Lumbares / Antineoplásicos Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Radiology Año: 2000 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Soluciones Esclerosantes / Neoplasias de la Columna Vertebral / Vértebras Torácicas / Etanol / Hemangioma / Vértebras Lumbares / Antineoplásicos Tipo de estudio: Diagnostic_studies / Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Radiology Año: 2000 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos