Circulating inflammatory cytokine levels in hemolytic uremic syndrome.

Litalien, C; Proulx, F; Mariscalco, M M; Robitaille, P; Turgeon, J P; Orrbine, E; Rowe, P C; McLaine, P N; Seidman, E

Litalien, C; Proulx, F; Mariscalco, M M; Robitaille, P; Turgeon, J P; Orrbine, E; Rowe, P C; McLaine, P N; Seidman, E.

Afiliación

Litalien C; Department of Pediatrics, Sainte-Justine Hospital, 3175 Chemin Côte Sainte-Catherine, Montréal, Québec, H3T-1C5, Canada.

Pediatr Nephrol ; 13(9): 840-5, 1999 Nov.

Article en En | MEDLINE | ID: mdl-10603133

RESUMEN

Experimental data suggest that the host's inflammatory response is involved in the pathophysiology of verotoxin-producing Escherichia coli (VTEC)-associated hemolytic uremic syndrome (HUS). We compared the circulating levels of pro- [interleukin (IL)-6, IL-8] and anti-inflammatory [IL-10 and IL-1 receptor antagonist (Ra)] mediators on enrollment among children with HUS due to E. coli O157:H7, according to the severity of renal dysfunction. The latter was evaluated by the occurrence of oligoanuria, the requirement for dialysis, and a glomerular filtration rate (GFR)

Asunto(s)

Citocinas/sangre; Escherichia coli/inmunología; Síndrome Hemolítico-Urémico/inmunología; Niño; Preescolar; Femenino; Tasa de Filtración Glomerular; Síndrome Hemolítico-Urémico/microbiología; Humanos; Lactante; Inflamación/microbiología; Interleucina-10/sangre; Interleucina-6/sangre; Interleucina-8/sangre; Masculino; Receptores de Interleucina-1/agonistas; Receptores de Interleucina-1/sangre

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citocinas / Escherichia coli / Síndrome Hemolítico-Urémico Límite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Pediatr Nephrol Asunto de la revista: NEFROLOGIA / PEDIATRIA Año: 1999 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Alemania

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