The deterioration of cardiovascular reflexes in Parkinson's disease.
Acta Neurol Scand
; 100(5): 296-9, 1999 Nov.
Article
en En
| MEDLINE
| ID: mdl-10536915
OBJECTIVES: We have investigated the deterioration of cardiovascular reflexes in Parkinson's disease. PATIENTS AND METHODS: In a group of 20 patients with Parkinson's disease (PD) and in a group of 10 age-matched control subjects a battery of cardiovascular reflex (CVR) tests (Valsalva manoeuvre, deep breathing test, handgrip test, orthostatic test) was repeated after 3 years. RESULTS: In PD patients at deep breathing test, at Valsalva manoeuvre and at orthostatic test the heart rate response decreased significantly (P<0.05). The impairment of systolic and diastolic blood pressure response at orthostatic test was significant as well (P < 0.005). At hand grip test no significant changes in heart rate and blood pressure response were found. In control subjects only heart rate response at orthostatic test decreased significantly after 3 years. CONCLUSION: Our results show progression of an impairment of sympathetic and parasympathetic control of the cardiovascular functions in patients with PD over a period of 3 years.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Enfermedades Cardiovasculares
/
Reflejo Anormal
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Neurol Scand
Año:
1999
Tipo del documento:
Article
País de afiliación:
Eslovenia
Pais de publicación:
Dinamarca