Incorporation of particulated bone implants in the facial skeleton.
Biomaterials
; 20(21): 2029-35, 1999 Nov.
Article
en En
| MEDLINE
| ID: mdl-10535814
The purpose of this study was to compare the regenerative response of autogenous cortical and cancellous bone chips and a natural particulate resorbable bone mineral (RBM) (Bio-Oss, Geistlich-Pharma, Wolhusen, Switzerland) in standardized bony defects relating paranasal sinuses to one another and to bone blocks. On 13 skeletally mature female goats four standardized critical-sized full thickness bone defects were made in the frontal bone overlying the frontal sinus. These defects were filled at random with cortical bone chips, cancellous bone chips, spongiosa granules of a RBM or left empty. Fluorochrome bone markers were injected subcutaneously 1 and 5 weeks after transplantation, and one week before the animals were killed. The animals were killed at 3, 6, 12 and 24 weeks after surgery. Autogenous cancellous bone chips is the material of choice for bridging a bony defect in the maxillofacial area where there is no need for mechanical strength. They heal in the same way as cancellous bone blocks do. Cortical bone chips are not reliable enough to be used as a solitary bone-grafting material under these conditions. A cortical block as a solitary implant gives better results. RBM granules as solitary implant in a critical-sized defect do not stimulate osteoconduction but give rise to an extensive osteoclastic activity stimulated by the mutual loose relation. A solid block of RBM is in a similar case more reliable.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sustitutos de Huesos
/
Implantes Experimentales
/
Implantes Absorbibles
/
Huesos Faciales
/
Prótesis Maxilofacial
/
Minerales
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Biomaterials
Año:
1999
Tipo del documento:
Article
País de afiliación:
Países Bajos
Pais de publicación:
Países Bajos