[Age-related changes of vertebral bone mineral density in Russian population]. / Vozrastnye izmeneniia mineral'noi plotnosti pozvonkov v norme u rossiiskoi populiatsii.
Vestn Rentgenol Radiol
; (6): 28-33, 1998.
Article
en Ru
| MEDLINE
| ID: mdl-10513247
Vertebral trabecular bone mineral density (BMD) was measured by quantitative computed tomography (QCT) in 1061 subjects (610 females and 451 males aged from 7 to 91 and from 12 to 89, respectively) with known history of diseases or taking medicines affecting bone metabolism. Peak BMD values in our patients were observed at the age of 20-29 years with further gradual decrement in men and more steep in women. Negative relationship between BMD and age was r = -0.991 for men and r = -0.968 for women. Analyzing BMD changes by decades we observed the largest decrement in men after 60 (13.1% for 60-69 and 14.1% for 70-79 years of age) and in women after 50 (22.5% for 50-59, 22.1% for 60-69 and 20.8% for 70-79 years) which was most probably due to decline in sex hormones production that is known to significantly influence bone metabolism. This was confirmed by BMD values three-phase approximation in women showing the lowest rate of calcium loss by trabecular bone in reproductive period (1.9 mg/cm3/yr) and the highest in perimenopause (3.98 mg/cm3/yr). Annual calcium loss in postmenopause was 2.22 mg/cm3.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Columna Vertebral
/
Envejecimiento
/
Densidad Ósea
Límite:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
/
Europa
Idioma:
Ru
Revista:
Vestn Rentgenol Radiol
Año:
1998
Tipo del documento:
Article
Pais de publicación:
Rusia