Prefrontal enlargement of CSF spaces in agoraphobia: a qualitative CT-scan study.

Wurthmann, C; Gregor, J; Baumann, B; Schwarz, A; Effenberger, O; Doehring, W; Bogerts, B

Wurthmann, C; Gregor, J; Baumann, B; Schwarz, A; Effenberger, O; Doehring, W; Bogerts, B.

Afiliación

Wurthmann C; Department of Psychiatry and Psychotherapy, Philippusstift Essen, FRG.

Prog Neuropsychopharmacol Biol Psychiatry ; 23(5): 823-30, 1999 Jul.

Article en En | MEDLINE | ID: mdl-10509377

RESUMEN

1. This CT study was designed to assess brain morphology in 21 patients with agoraphobia and 21 normal control subjects matched for age and sex. 2. Internal and external CSF spaces were evaluated by qualitative assessment on a 3-point scale (normal, questionable, abnormal). 3. Patients showed bilateral enlargement of prefrontal CSF spaces (p < .05). The rating abnormal" was given in the left hemisphere to 6 (28.6%) of the patients, to 4 (19%) of the patients in the right hemisphere, but to none (0%) of the normal controls. 4. These findings suggest that alterations in brain morphology are involved in the etiology of agoraphobia.

Asunto(s)

Agorafobia/líquido cefalorraquídeo; Agorafobia/diagnóstico por imagen; Corteza Prefrontal/diagnóstico por imagen; Adulto; Agorafobia/psicología; Corteza Cerebral/diagnóstico por imagen; Femenino; Humanos; Masculino; Escalas de Valoración Psiquiátrica; Tomografía Computarizada por Rayos X

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Prefrontal / Agorafobia Tipo de estudio: Qualitative_research Límite: Adult / Female / Humans / Male Idioma: En Revista: Prog Neuropsychopharmacol Biol Psychiatry Año: 1999 Tipo del documento: Article Pais de publicación: Reino Unido

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