Melanotic craniopharyngioma: a report of two cases.

Harris, B T; Horoupian, D S; Tse, V; Herrick, M K

Harris, B T; Horoupian, D S; Tse, V; Herrick, M K.

Afiliación

Harris BT; Department of Pathology, Neuropathology Rm. R241, 300 Pasteur Drive, Stanford University School of Medicine, Stanford, CA 94305-5324, USA. bharris@pathology.stanford.edu

Acta Neuropathol ; 98(4): 433-6, 1999 Oct.

Article en En | MEDLINE | ID: mdl-10502051

RESUMEN

We report a 74-year-old woman and a 50-year-old woman with similar histories of headache and visual disturbance who were found to have adamantinomatous craniopharyngiomas which contained melanin pigment. This finding was confirmed by the Masson Fontana method and ultrastructural studies. These are only the second and third cases reported describing melanin pigment within a craniopharyngioma. The finding of melanin in craniopharyngiomas attests to their similarities with odontogenic tumors of the jaw, which can also contain melanin pigment and also supports the hypothesis that the histogenesis of these neoplasms derives from the vestiges of Rathke's pouch epithelium.

Asunto(s)

Craneofaringioma/metabolismo; Craneofaringioma/patología; Melaninas/metabolismo; Neoplasias Hipofisarias/metabolismo; Neoplasias Hipofisarias/patología; Anciano; Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/patología; Femenino; Humanos; Microscopía Electrónica; Persona de Mediana Edad

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hipofisarias / Craneofaringioma / Melaninas Límite: Aged / Female / Humans / Middle aged Idioma: En Revista: Acta Neuropathol Año: 1999 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania

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