A novel human gene, encoding a potential membrane protein conserved from yeast to man, is strongly expressed in testis and cancer cell lines.
Cytogenet Cell Genet
; 85(3-4): 217-20, 1999.
Article
en En
| MEDLINE
| ID: mdl-10449901
We have characterized a novel human gene (C14orf1) which codes for a polypeptide homologous to the yeast protein Yer044c. Both the human and yeast proteins are predicted to be highly basic and to present several potential, evolutionarily conserved, transmembrane domains. C14orf1 mRNA was found to be particularly abundant in the adult testis and in several cancer cell lines. The gene maps to chromosome band 14q24. Further investigations should be performed to understand the role of C14orf1 in the testis and the significance of its strong expression in the cell lines studied here.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Testículo
/
Secuencia Conservada
/
Proteínas de la Membrana
/
Proteínas de Neoplasias
/
Neoplasias
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Cytogenet Cell Genet
Año:
1999
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Suiza