Positron emission tomography neuroreceptor imaging as a tool in drug discovery, research and development.

Burns, H D; Hamill, T G; Eng, W S; Francis, B; Fioravanti, C; Gibson, R E

Burns, H D; Hamill, T G; Eng, W S; Francis, B; Fioravanti, C; Gibson, R E.

Afiliación

Burns HD; Department of Pharmacology, Merck Research Laboratories, WP44C-2, Sumneytown Pike, West Point, PA 19438, USA. donald_burns@merck.com

Curr Opin Chem Biol ; 3(4): 388-94, 1999 Aug.

Article en En | MEDLINE | ID: mdl-10419855

RESUMEN

Improved communication and cooperation between research-driven drug companies and academic positron emission tomography (PET) centers, coupled with improvements in PET camera resolution, the availability of small animal PET cameras and a growing list of neuroreceptor-specific PET tracers, have all contributed to a substantial increase in the use and value of PET as a tool in central nervous system drug discovery and development.

Asunto(s)

Diseño de Fármacos; Células Receptoras Sensoriales/metabolismo; Tomografía Computarizada de Emisión/métodos; Animales; Sistema Nervioso Central/diagnóstico por imagen; Sistema Nervioso Central/efectos de los fármacos; Sistema Nervioso Central/metabolismo; Humanos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Receptoras Sensoriales / Diseño de Fármacos / Tomografía Computarizada de Emisión Límite: Animals / Humans Idioma: En Revista: Curr Opin Chem Biol Asunto de la revista: BIOQUIMICA Año: 1999 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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