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Apraxia in corticobasal degeneration.
Jacobs, D H; Adair, J C; Macauley, B; Gold, M; Gonzalez Rothi, L J; Heilman, K M.
Afiliación
  • Jacobs DH; Memory Disorders Clinic, Orlando Regional Healthcare System, Orlando, Florida 32608, USA.
Brain Cogn ; 40(2): 336-54, 1999 Jul.
Article en En | MEDLINE | ID: mdl-10413565
Corticobasal degeneration (CBD) is a degenerative disease that often presents with an asymmetric progressive ideomotor limb apraxia. Some apraxic subjects may fail to perform skilled purposive movements on command because they have lost the memories or representations that specify how these movements should be performed (representational deficit). In contrast, other apraxic subjects may have the movement representations but are unable to utilize the information contained in them to execute skilled purposive movements (production-execution deficit). To learn if the apraxic deficit in CBD is induced by a representational or a production-execution deficit, we tested three nondemented subjects with CBD on tasks requiring production of meaningful or meaningless gestures to command, gesture imitation, gesture discrimination, and novel gesture learning. A fourth subject with incomplete data also is presented. The results suggest that the apraxia associated with CBD is initially induced by a production-execution defect with relative sparing of the movement representations.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apraxias / Ganglios Basales / Corteza Cerebral / Degeneración Nerviosa Tipo de estudio: Diagnostic_studies Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Brain Cogn Año: 1999 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apraxias / Ganglios Basales / Corteza Cerebral / Degeneración Nerviosa Tipo de estudio: Diagnostic_studies Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Brain Cogn Año: 1999 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos