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Stimulation of early embryonic development in cattle by coculture with surfactant.
Osada, H; Watanabe, Y; Fujii, T K; Tsunoda, I; Tsubata, K; Satoh, K.
Afiliación
  • Osada H; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan.
J Assist Reprod Genet ; 16(6): 310-4, 1999 Jul.
Article en En | MEDLINE | ID: mdl-10394527
PURPOSE: Our purpose was to determine the efficacy of Surfacten, a bovine pulmonary surfactant, on the maturation of in vitro bovine ova. METHODS: We used Surfacten as a supplement to the coculture media both at the onset of coculture and after cleavage in bovine ova had been determined. The controls received no Surfacten. RESULTS: The maturation rate in bovine embryos to the blastocyst stage statistically improved (P < 0.05) in the series in which Surfacten was added to the media at the onset of coculture, compared with the controls and the series in which Surfacten was added after cleavage had been determined. CONCLUSIONS: Surfacten, a commercially available surfactant which is a naturally occurring phospholipid that dramatically increases in the cervical mucus and the ampullaris of the oviduct at or near the time of ovulation, improves the maturation of bovine embryos in vitro by making the coculture medium approach the conditions found in the oviducts.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Óvulo / Células Tecales / Surfactantes Pulmonares / Fertilización In Vitro / Desarrollo Embrionario y Fetal / Células de la Granulosa Límite: Animals / Female / Humans Idioma: En Revista: J Assist Reprod Genet Asunto de la revista: GENETICA / MEDICINA REPRODUTIVA Año: 1999 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Óvulo / Células Tecales / Surfactantes Pulmonares / Fertilización In Vitro / Desarrollo Embrionario y Fetal / Células de la Granulosa Límite: Animals / Female / Humans Idioma: En Revista: J Assist Reprod Genet Asunto de la revista: GENETICA / MEDICINA REPRODUTIVA Año: 1999 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos