Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino[4,3-b]indole-4-carboxylic acids.

Palluotto, F; Carotti, A; Casini, G; Ferappi, M; Rosato, A; Vitali, C; Campagna, F

Palluotto, F; Carotti, A; Casini, G; Ferappi, M; Rosato, A; Vitali, C; Campagna, F.

Afiliación

Palluotto F; Dipartimento Farmacochimico, Università di Bari, Italy.

Farmaco ; 54(3): 191-4, 1999 Mar 31.

Article en En | MEDLINE | ID: mdl-10371032

RESUMEN

The in vitro antibacterial and antifungal activities of a series of pyridazinoindolonic acids II against some selected representative of Gram-positive, Gram-negative bacteria and fungi have been investigated. Some interesting observations among the structural features necessary for high antibacterial activity are presented and discussed.

Asunto(s)

Antibacterianos/farmacología; Indoles/farmacología; Piridazinas/farmacología; Antibacterianos/síntesis química; Indoles/síntesis química; Estructura Molecular; Piridazinas/síntesis química

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Indoles / Antibacterianos Idioma: En Revista: Farmaco Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 1999 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Francia

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