Brainstem auditory evoked response in newborns with hyperbilirubinemia.
Indian Pediatr
; 35(6): 513-8, 1998 Jun.
Article
en En
| MEDLINE
| ID: mdl-10216645
OBJECTIVE: To determine the initial Brainstem Auditory Evoked Response (BAER) abnormalities in neonates with hyperbilirubinemia and the possible reversibility of abnormal BAER after therapy. DESIGN: Prospective cohort study. SETTING: Tertiary care hospital. SUBJECTS: 30 term neonates with hyperbilirubinemia (S. bilirubin < 15 mg/dl) as cases and 25 normal term neonates as controls. METHODS: Duration of study was from August 1995 to August 1996. BAER were recorded before therapy at peak hyperbilirubinemia, after therapy, and the age of 2-4 months using electric response audiometer (Nihon Neuropack Four Machine). Denver Development Screening Test (Denver II) was performed at 1 year of age. RESULTS: Seventeen out of thirty (56.7%) neonates with hyperbilirubinemia showed abnormalities on initial BAER. Commonest abnormality seen was raised threshold of wave V in 12 neonates (40%). Other abnormalities observed were absence of all waves at 90 dB (23.3%), prolongation of latencies of various waves (26.7%) and prolongation of various intervals (26.7%). Abnormalities in BAER correlated significantly with bilirubin level. After therapy abnormalities reverted back to normal in 10 cases but persisted in 7 out of 17 (41.17%) cases with initial abnormal BAER. Development screening at 1 yr was abnormal in 3 infants all of whom had persistent abnormalities in BAER. CONCLUSION: Serial BAER is a useful, non invasive tool to detect neurodevelopment delay secondary to neonatal hyperbilirubinemia.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Potenciales Evocados Auditivos del Tronco Encefálico
/
Pérdida Auditiva Sensorineural
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Ictericia Neonatal
Tipo de estudio:
Observational_studies
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Risk_factors_studies
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Screening_studies
Límite:
Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Revista:
Indian Pediatr
Año:
1998
Tipo del documento:
Article
Pais de publicación:
India