Antiperinuclear factor and antibodies to the stratum corneum of rat esophagus in juvenile idiopathic arthritis.

Serra, C R; Rodrigues, S H; Sztajnbok, F R; Silva, N P; Andrade, L E

Serra, C R; Rodrigues, S H; Sztajnbok, F R; Silva, N P; Andrade, L E.

Afiliación

Serra CR; Division of Rheumatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.

J Pediatr ; 134(4): 507-9, 1999 Apr.

Article en En | MEDLINE | ID: mdl-10190929

RESUMEN

We analyzed the frequency and clinical correlates of antiperinuclear factor (APF) and antibodies to the stratum corneum of rat esophagus in 86 children with juvenile idiopathic arthritis (JIA), 32 children with juvenile systemic lupus erythematosus, and 52 healthy children. Forty-two patients with JIA (49%) were positive for APF. No association was observed between APF and current age, sex, JIA subtype, age at disease onset, or disease duration. APF was found in one patient with juvenile systemic lupus erythematosus and in no healthy child. Antibodies to the stratum corneum of rat esophagus were detected in 3 patients with polyarticular JIA. APF may be a valuable tool in the differential diagnosis of JIA.

Asunto(s)

Anticuerpos Antinucleares/sangre; Anticuerpos/sangre; Artritis Juvenil/sangre; Queratinas/inmunología; Animales; Preescolar; Femenino; Técnica del Anticuerpo Fluorescente Indirecta; Humanos; Lupus Eritematoso Sistémico/sangre; Masculino; Ratas; Valores de Referencia; Factor Reumatoide/sangre

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Juvenil / Anticuerpos Antinucleares / Queratinas / Anticuerpos Límite: Animals / Child, preschool / Female / Humans / Male Idioma: En Revista: J Pediatr Año: 1999 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos

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