Molecular genetics diagnostic applications in oncology.
Clin Lab Sci
; 4(5): 284-6, 1991.
Article
en En
| MEDLINE
| ID: mdl-10149418
The use of lineage and cytogenetic probes in diagnosis of oncologic disorders is reviewed. The presence of rearranged bands via Southern blot analysis may generate diagnostic support of hematopoietic malignancy in several instances. DNA probes can be used to demonstrate clonality, reveal lineage characteristics, or identify specific chromosomal aberrations. Lineage probes detect genetic events during normal lymphocyte differentiation, while cytogenetic probes detect a malignant characteristic. The number of translocations detectable using DNA probes will likely expand in the future.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sondas de ADN
/
Sondas Moleculares
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Clin Lab Sci
Asunto de la revista:
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Año:
1991
Tipo del documento:
Article
Pais de publicación:
Estados Unidos