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New cytotoxic oxygenated fucosterols from the brown alga Turbinaria conoides.
Sheu, J H; Wang, G H; Sung, P J; Duh, C Y.
Afiliación
  • Sheu JH; Department of Marine Resources, National Sun Yat-Sen University, Kaohsiung, Taiwan 804, Republic of China.
J Nat Prod ; 62(2): 224-7, 1999 Feb.
Article en En | MEDLINE | ID: mdl-10075746
Fucosterol (1), 24xi-hydroperoxy-24-vinylcholesterol (2), 29-hydroperoxystigmasta-5,24(28)-dien-3beta-ol (3), 24-ethylcholesta-4,24(28)-dien-3-one (4), 24xi-hydroperoxy-24-ethylcholesta-4,28(29)-dien-3-one (5), 24-ethylcholesta-4,24(28)-dien-3,6-dione (6), 24xi-hydroperoxy-24-ethylcholesta-4,28(29)-dien-3,6-di one (7), 6beta-hydroxy-24-ethylcholesta-4,24(28)-dien-3-one (8), and 24xi-hydroperoxy-6beta-hydroxy-24-ethylcholesta-4,28(2 9)-dien-3-one (9) were isolated from the marine brown alga Turbinaria conoides. The structures of these compounds were established by spectral analysis. Isolated for the first time from a natural source, the oxygenated fucosterols 4-9 exhibit cytotoxicity against various cancer cell lines.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxígeno / Estigmasterol / Phaeophyceae / Antineoplásicos Fitogénicos Idioma: En Revista: J Nat Prod Año: 1999 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Buscar en Google
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxígeno / Estigmasterol / Phaeophyceae / Antineoplásicos Fitogénicos Idioma: En Revista: J Nat Prod Año: 1999 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos