A developmentally regulated lectin in Bufo arenarum embryos
Braz. j. med. biol. res
; 20(6): 749-53, 1987. ilus, tab
Article
en En
| LILACS
| ID: lil-77428
Biblioteca responsable:
BR26.1
ABSTRACT
We report the levels of an endogenous beta-galactoside lectin activity from Bufo arenarum whole embryos extracts and specific inhibition by saccharides at different developmental stages. Specific activity measured against trypsinized rabbit red blood cells showed relatively high and fluctualting levels during early stages (up to about 76 h post-fertilization) which fell to significantly lower and more constant values at late stages (77-264 h post-fertilization). Lactose is the most potent inhibitor of this lectin activithy, and saccharides having alpha-galactoside configurations are weaker inhibitors. At the last embryonic stage, the agglutinating activity showed a different sugar specificity which suggests either the modification of the preexistent lectin or the sybthesis of another type of lectin. The possible physiological roles of these in the blockage of polyspermy or in embryonic cell-cell interactions are discussed
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Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Bufo arenarum
/
Embrión no Mamífero
/
Hemaglutininas
Límite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
1987
Tipo del documento:
Article
Pais de publicación:
Brasil