Respiratory syncytial virus, infants and intensive therapy
Braz. j. infect. dis
; 16(1): 86-89, Jan.-Feb. 2012. tab
Article
en En
| LILACS
| ID: lil-614557
Biblioteca responsable:
BR1.1
ABSTRACT
The aims of this study were to determine the presence of respiratory syncytial virus (RSV) and to assess the clinical features of the disease in infants with acute low respiratory tract infection hospitalized at pediatric intensive care units (PICU) of two university teaching hospitals in São Paulo State, Brazil. Nasopharyngeal secretions were tested for the RSV by the polymerase chain reaction. Positive and negative groups for the virus were compared in terms of evolution under intensive care (mechanical pulmonary ventilation, medications, invasive procedures, complications and case fatality). Statistical analysis was performed using the Mann Whitney and Fisher's exact tests. A total of 21 infants were assessed, 8 (38.1 percent) of whom were positive for RSV. The majority of patients were previously healthy while 85.7 percent required mechanical pulmonary ventilation, 20/21 patients presented with at least one complication, and the fatality rate was 14.3 percent. RSV positive and negative groups did not differ for the variables studied. Patients involved in this study were critically ill and needed multiple PICU resources, independently of the presence of RSV. Further studies involving larger cohorts are needed to assess the magnitude of the impact of RSV on the clinical evolution of infants admitted to the PICU in our settings.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Virus Sincitiales Respiratorios
/
Infecciones por Virus Sincitial Respiratorio
Límite:
Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Revista:
Braz. j. infect. dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2012
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil