Changes in myocardial and coronary sinus blood oxygen tension induced by asphysia and reoxygenation

Cicogna, Antonio Carlos; Spadaro, Joel; Tucci, Paulo José Ferreira; Bregagnollo, Edson A; Rodrigues, Maria Marquesan; Curi, Paulo Roberto; Lucchiari, Pedro Hélio

Cicogna, Antonio Carlos; Spadaro, Joel; Tucci, Paulo José Ferreira; Bregagnollo, Edson A; Rodrigues, Maria Marquesan; Curi, Paulo Roberto; Lucchiari, Pedro Hélio.

Braz. j. med. biol. res ; 21(3): 585-90, Mar. 1988. tab

Article en En | LILACS | ID: lil-60269

Biblioteca responsable: BR1.1

ABSTRACT

ABSTRACT

This study analyzes variations of oxygen tension induced by asphyxia in the myocardium (MpO2) and coronary sinus blood (CSpO2) of the anesthetized open-chest dog. Oxygen tension was measured polarographically and arterial blood pressure and coronary blood flow were recorded simultaneously. Asphyxia increased arterial pressure and coronary blood flow but decreased both MpO2 and CSpO2. During the reoxygenation phase, arterial pressure and coronary flow decreased gradually. Reoxygenation induced a rapid but transient increase in CSpO2 above control levels. In contrast, MpO2 returned gradually to the basal state. The mechanisms(s) involved in the differential effects of asphyxia followed by reoxygenation on MpO2 and CSpO2 remain to be elucidated

Asunto(s)

Perros; Animales; Masculino; Asfixia/fisiopatología; Enfermedad Coronaria/fisiopatología; Vasos Coronarios; Miocardio/metabolismo; Consumo de Oxígeno; Asfixia/complicaciones; Presión Sanguínea; Circulación Coronaria; Hipoxia/etiología

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Colección: 01-internacional Base de datos: LILACS Asunto principal: Consumo de Oxígeno / Asfixia / Enfermedad Coronaria / Vasos Coronarios / Miocardio Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Braz. j. med. biol. res Asunto de la revista: BIOLOGIA / MEDICINA Año: 1988 Tipo del documento: Article Pais de publicación: Brasil

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