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Chronic graft versus host disease: a scleroderma-like case report
Pereira, Claudio Maranhão; Melo, Laura Guimarães; Gasparetto, Patrícia Freire; Corrêa, Maria Elvira P.
Afiliación
  • Pereira, Claudio Maranhão; Paulista University. School of Dentistry. Goiania. BR
  • Melo, Laura Guimarães; Paulista University. School of Dentistry. Goiania. BR
  • Gasparetto, Patrícia Freire; Paulista University. School of Dentistry. Goiania. BR
  • Corrêa, Maria Elvira P; State University of Campinas. Hematology and Hemotherapy Center. Dentistry Ambulatory. Sao Paulo. BR
RSBO (Impr.) ; 8(2): 236-239, jun. 2011. ilus
Article en En | LILACS | ID: lil-591758
Biblioteca responsable: BR1.1
ABSTRACT

INTRODUCTION:

Chronic graft versus host disease (cGVHD) is the most common consequence of allogeneic bone marrow transplantation, and it is associated with morbidity and mortality. Oral manifestations are diagnosed in approximately 80 percent of patients with chronic GVHD.

OBJECTIVE:

To present a case of chronic GVHD with scleroderma-like lesions in skin and oral cavity CASE REPORT A 27-year-old female was admitted, in a Hematology Center, in 1997, with previous diagnosis of chronic myeloid leukemia since 1994. Over past four months after allogeneic BTM she developed cGVHD in eyes, mouth, liver, lungs and skin. The patient presented sclerotic skin changes, hyperkeratosis of hands and xerophthalmia.

CONCLUSION:

Clinical manifestations of chronic GVHD are similar to autoimmune collagen vascular disease and the two main types of cutaneous chronic GVHD are lichenoid and sclerodermatous.
Palabras clave
Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Idioma: En Revista: RSBO (Impr.) Asunto de la revista: ODONTOLOGIA Año: 2011 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Idioma: En Revista: RSBO (Impr.) Asunto de la revista: ODONTOLOGIA Año: 2011 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil