Marcadores eléctricos no invasores en pacientes con síndrome de Brugada / Non-invasive electrical markers in patients with the Brugada syndrome
Arch. cardiol. Méx
; 76(1): 52-58, ene.-mar. 2006.
Article
en Es
| LILACS
| ID: lil-569527
Biblioteca responsable:
BR1.1
ABSTRACT
Throughout the 13 years of recognizing the Brugada syndrome as a separate entity, there has been a search for invasive and non-invasive markers for detecting risk of life-threatening arrhythmic events, particularly for asymptomatic individuals in whom the first manifestation may be sudden cardiac death. Hence, the preclinical diagnosis is pivotal for adequate and timely preventive measures. The objective of this study was to compare various non-invasive markers to characterize and stratify patients at risk. Late potentials, QT interval, QT dispersion, and heart variability were analyzed over a two-year period, in 20 patients (17 men and 3 women) with the Brugada syndrome (symptomatic and asymptomatic) and compared with 20 normal individuals similar in age and gender (control group). Late potentials were present in 80% of patients versus 5% in the control group (p < 0.0001); all of these with recurrent episodes had late potentials. In conclusion, this is the most important non-invasive marker for risk stratification, recurrences and inducibility of malignant arrhythmias during electrophysiological testing. Markers, invasive and non-invasive, should be considered integrally, for a better diagnostic and prognostic approach to reality.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Bloqueo de Rama
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Arch. cardiol. Méx
Asunto de la revista:
CARDIOLOGIA
Año:
2006
Tipo del documento:
Article
País de afiliación:
Cuba
Pais de publicación:
México