Factores pronósticos, evolución y mortalidad en el adulto inmunocompetente hospitalizado por neumonía neumocócica adquirida en la comunidad / Prognostic factors and mortality in immunocompetent adult patients hospitalized with community-acquired pneumococcal pneumonia
Rev. méd. Chile
; 137(12): 1545-1552, dic. 2009. tab
Article
en Es
| LILACS
| ID: lil-543130
Biblioteca responsable:
BR1.1
ABSTRACT
Background:
Streptococcus pneumoniae is the main cause of community-acquired pneumonia in adults.Aim:
To describe baseline characteristics, risk factors and clinical outcomes of adult patients hospitalized with pneumococcal pneumonia. Material andmethods:
Prospective study of adult patients admitted for a community acquired pneumonia in a clinical hospital. Immune deficient patients and those with a history of a recent hospitalization were excluded.Results:
One hundred fifty one immuno-competent patients, aged 16 to 92 years, 58 percent males, were studied. Seventy-five percent had other diseases, 26 percent were admitted to the intensive care unit and 9 percent needed mechanical ventilation. There were no differences in clinical features, ICU admission or hospital length of stay among bacteremic and non-bacteremic patients. Thirty days lethality for bacteremic and non-bacteremic patients was 10.9 percent and 11.5 percent, respectively. The predictive values for lethality of Fine pneumonia severity index and CURB-65 (Confusion, Urea nitrogen, Respiratory rate, Blood pressure, 65 years of age and older) had an area under the ROC curve of 0.8 and 0.69, respectively. Multivariate analysis disclosed blood urea nitrogen over 30 mg/ dL (odds ratio (OR), 6.8), need for mechanical ventilation (OR, 7.4) and diastolic blood pressure below 50 mmHg (OR, 3.9), as significant independent predictors of death.Conclusions:
Pneumococcal pneumonia was associated with a substantial rate of complications and mortality. Clinical presentation and outcome did not differ significantly among patients with and without bacteremia.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Neumonía Neumocócica
/
Mortalidad Hospitalaria
/
Bacteriemia
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Región como asunto:
America do sul
/
Chile
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Chile
Pais de publicación:
Chile