Your browser doesn't support javascript.
loading
Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables / Diagnostic value of frozen section biopsy during surgery for breast lesions or neoplasms
Bellolio J, Enrique; Guzmán G, Pablo; Orellana C, Juan; Roa S, Juan Carlos; Villaseca H, Miguel; Araya O, Juan Carlos; Tapia E, Oscar; ineda N, Viviana.
Afiliación
  • Bellolio J, Enrique; Universidad de La Frontera. Departamento de Anatomía Patológica. CL
  • Guzmán G, Pablo; Universidad de La Frontera. Departamento de Anatomía Patológica. CL
  • Orellana C, Juan; Universidad de La Frontera. Facultad de Medicina. Centro de Excelencia, Capacitación, Gestión e Investigación para la Salud Basada en Evidencias (CIGES). CL
  • Roa S, Juan Carlos; Universidad de La Frontera. Departamento de Anatomía Patológica. CL
  • Villaseca H, Miguel; Universidad de La Frontera. Departamento de Anatomía Patológica. CL
  • Araya O, Juan Carlos; Universidad de La Frontera. Departamento de Anatomía Patológica. CL
  • Tapia E, Oscar; Universidad de La Frontera. Departamento de Anatomía Patológica. CL
  • ineda N, Viviana; Universidad de La Frontera. Departamento de Cirugía y Traumatología. Temuco. CL
Rev. méd. Chile ; 137(9): 1173-1178, sep. 2009. tab
Article en Es | LILACS | ID: lil-534018
Biblioteca responsable: BR1.1
ABSTRACT

Background:

During the surgical treatment of breast neoplasms (benign or malignant), frozen section biopsy is frequently requested to assess the kind of lesion and determine the surgical margins.

Aim:

To assess the diagnostic yield of frozen section breast biopsy. Material and

methods:

AH the pathological reports of frozen section biopsies and definitive biopsies of 337 women aged 26 to 88 years, operated for suspected breast neoplasms between 2002 and 2006, were reviewed. The sensitivity, specificity and predictive value of frozen section biopsy, were calculated using the definitive biopsy as the gold standard.

Results:

The definitive biopsy confirmed the presence of cancer in 290 women (86 percent). There were two false negative (0.59 percent) and no false positive frozen section biopsies for cancer detection. The sensibility for cancer detection was 99.3 percent and the specificity 100 percent. The positive predictive value was 100 percent and the negative predictive value 96.1 percent. The diagnosis of phyllodes tumor was missed by frozen section biopsy in three cases. The margins were informed in the 258 frozen section biopsies (79 percent) and in 59 cases (18 percent), these were positive for cancer.

Conclusions:

Frozen section biopsy is useful and reliable for cancer detection and margin status assessment in breast cancer surgery (RevMéd Chile 2009; 137 1173-8).
Asunto(s)
Palabras clave
Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Biopsia / Neoplasias de la Mama / Secciones por Congelación / Cuidados Intraoperatorios Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans Idioma: Es Revista: Rev. méd. Chile Asunto de la revista: MEDICINA Año: 2009 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Chile
Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Biopsia / Neoplasias de la Mama / Secciones por Congelación / Cuidados Intraoperatorios Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans Idioma: Es Revista: Rev. méd. Chile Asunto de la revista: MEDICINA Año: 2009 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Chile