Effects of Androctonus crassicauda (Olivier, 1807) (Scorpiones: Buthidae) venom on rat metabolism
J. venom. anim. toxins incl. trop. dis
; J. venom. anim. toxins incl. trop. dis;14(1): 45-57, 2008. tab
Article
en En
| LILACS, VETINDEX
| ID: lil-479338
Biblioteca responsable:
BR68.1
ABSTRACT
Scorpions are venomous arthropods of the Arachnida class and are considered relatives of spiders, ticks and mites. There is not any study about the biochemical effects of Androctonus crassicauda (Olivier, 1807) venom. Therefore, in the present study, we aimed at evaluating the toxicity of the venom from A. crassicauda, which is responsible for a number of deaths of infants, children and adults in tropical and subtropical countries. For this purpose, rats (n=35) were divided into seven groups of five animals each; venom solutions (250µg/kg) were subcutaneously injected into rats; blood samples were taken from each animal at various times; and serum biochemical parameters were measured (levels of total proteins, total bilirubin, albumin, globulin, urea, creatinine, uric acid, glucose, cholesterol, triglycerides, sodium, chlorine, potassium and calcium, and the activity of the enzymes alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase). Serum levels of glucose, cholesterol, aspartate aminotransferase, alanine aminotransferase and uric acid increased in envenomed animals, compared to controls. There was a statistically positive correlation between Na+ and Cl- ions.(AU)
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
/
VETINDEX
Asunto principal:
Venenos de Escorpión
/
Escorpiones
/
Androctonus
/
Toxicidad
/
L-Lactato Deshidrogenasa
Límite:
Animals
Idioma:
En
Revista:
J. venom. anim. toxins incl. trop. dis
Asunto de la revista:
TOXICOLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Turquía
Pais de publicación:
Brasil