Evolución de comorbilidades metabólicas asociadas a obesidad después de cirugía bariátrica / Effects of gastric bypass on weight, blood glucose, serum lipid levels and arterial blood pressure in obese patients
Rev. méd. Chile
; 133(5): 511-516, mayo 2005. ilus, tab
Article
en Es
| LILACS
| ID: lil-429051
Biblioteca responsable:
BR1.1
ABSTRACT
Background:
Type 2 diabetes, hypertension and serum lipid abnormalities are common among obese people and they should improve with weight reduction.Aim:
To study the outcome of these abnormalities after bariatric surgery in morbid obesity patients. Material andmethods:
Two hundred thirty two morbid obese patients subjected to gastric bypass, were evaluated in the preoperative period and every three months after surgery, during a minimum of 12 months. Clinical evolution, blood glucose, serum insulin, insulin resistance measured with the homeostasis model assessment (HOMA) and serum lipid levels were analyzed.Results:
In the preoperative period, 17% had type 2 diabetes, 49% had abnormal serum lipid levels and 25% had high blood pressure. Sixty six percent had at least one of these abnormalities and 20% had more than one. During follow up, body mass index decreased from 44 to 29.3 kg/m2. Total and HDL cholesterol, blood glucose and insulin resistance significantly decreased from the third month after surgery. Diabetes disappeared in 97% of diabetic subjects, blood pressure normalized in 53% of subjects with hypertension and serum lipid levels returned to normal in 88% of subjects with dyslipidemia.Conclusions:
Gastric bypass in morbid obese patients achieves a significant and important weight reduction that results in significant reductions in the frequency of diabetes, dyslipidemia and hypertension among operated obese subjects.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Obesidad Mórbida
/
Derivación Gástrica
/
Dislipidemias
/
Hipertensión
Tipo de estudio:
Observational_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2005
Tipo del documento:
Article
País de afiliación:
Chile
Pais de publicación:
Chile