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Human papillomavirus infection in Rio de Janeiro, Brazil: a retrospective study
Carvalho, M. O. O; Carestiato, F. N; Perdigão, P. H; Xavier, M. P. P. T; Silva, K. C; Botelho, M. O; Oliveira, L. H. S; Cavalcanti, S. M. B.
Afiliación
  • Carvalho, M. O. O; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Carestiato, F. N; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Perdigão, P. H; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Xavier, M. P. P. T; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Silva, K. C; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Botelho, M. O; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Oliveira, L. H. S; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
  • Cavalcanti, S. M. B; Universidade Federal Fluminense. Biomedical Institute. Departmemt of Microbiology and Parasitology. Rio de Janeiro. BR
Braz. j. infect. dis ; Braz. j. infect. dis;9(5): 398-404, Oct. 2005. tab
Article en En | LILACS | ID: lil-419649
Biblioteca responsable: BR1.1
RESUMO
There is considerable data to support a central role for human papillomavirus (HPV) in the etiology of cervical cancer. More than a 100 HPV types have been described, and 40 have been isolated from benign and malignant genital lesions. Consequently, there is strong motivation to evaluate HPV testing for cervical cancer screening. Few studies concerning the natural history of HPV infection have been conducted in the state of Rio de Janeiro. We determined the prevalence of HPV types in female genital lesions by using Hybrid Capture Assay (HCA) and we retrospectively analyzed the course of HPV infection. Our sample included 788 women attended at Laboratórios Sérgio Franco. The average age of the participants was 29.6 years. HPV prevalence and cytological diagnosis were determined. The overall prevalence of HPV DNA in the study group was 50.1 percent (395/788), ranging from 25 percent (NORMAL) to 100 percent in high-grade intraepithelial lesions (HSIL). High risk HPV was found in 12 percent inflammatory, 58.3 percent HPV, 63.2 percent LSIL and 100 percent HSIL. A retrospective analysis of 78 patients showed that 22 presented persistent lesions, 2 had progressive lesions, 4 had regressive lesions, 13 showed latent infections, 18 were transiently infected and 19 were submitted to curative treatment. No cases of cancer were registered in this population, which can afford private medical care and regular follow-up exams. We suggest that HCA be used in specific cases involving persistent and recurrent lesions.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Papillomaviridae / Frotis Vaginal / Displasia del Cuello del Útero / Neoplasias del Cuello Uterino / Tamizaje Masivo / Infecciones por Papillomavirus Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Adolescent / Adult / Child / Female / Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2005 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Papillomaviridae / Frotis Vaginal / Displasia del Cuello del Útero / Neoplasias del Cuello Uterino / Tamizaje Masivo / Infecciones por Papillomavirus Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Adolescent / Adult / Child / Female / Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2005 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil