Sensibilidad antimicrobiana y caracterización de cepas de Streptococcus pyogenes aisladas de un brote de escarlatina / Antimicrobial sensitivity and characterization of Streptococcus pyogenes strains isoleated from a scarlatina outbreak
Salud pública Méx
; 44(5): 437-441, sept.-oct. 2002.
Article
en Es
| LILACS
| ID: lil-331695
Biblioteca responsable:
MX1.1
RESUMEN
OBJECTIVE:
To evaluate the in vitro activities of 13 antimicrobial agents against 47 group A Streptococcus pyogenes (GAS) strains, and to determine the presence of genes encoding streptococcal pyrogenic exotoxin A (SpeA) and the M-protein serotypes. MATERIALS ANDMETHODS:
A cross-sectional study was conducted at Centro de Salud Dr. JosÚ Castro Villagrana, during a scarlet fever outbreak occurring between December 1999 and January 2000, among 137 children at Colegio EspÝritu de AmÚrica. Minimum Inhibitory Concentrations (MICs) were obtained by the semiautomated microdilution method. Automated DNA sequencing was used for analysis of sequence variation in genes encoding the M protein, and SpeA.RESULTS:
All strains were sensitive to betalactams and clindamycin. Six (12.7) were resistant to erythromycin. The M2 type was the most frequently isolated GAS (27); almost all (96) bacteria with the SpeA gene had the gene encoding the M2 protein.CONCLUSIONS:
The recent resurgence of GAS infections calls for molecular epidemiology research and studies on the sensitivity to macrolides and beta-lactams.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Escarlatina
/
Streptococcus pyogenes
/
Resistencia a Medicamentos
/
Brotes de Enfermedades
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Región como asunto:
Mexico
Idioma:
Es
Revista:
Salud pública Méx
Asunto de la revista:
SAUDE PUBLICA
Año:
2002
Tipo del documento:
Article
País de afiliación:
México
Pais de publicación:
México