Axonal degeneration in association with carpal tunnel syndrome
Arq. neuropsiquiatr
; Arq. neuropsiquiatr;61(1): 48-50, mar. 2003. tab
Article
en En
| LILACS
| ID: lil-331157
Biblioteca responsable:
BR1.1
RESUMO
Median nerve entrapment in the palm to wrist segment is known as carpal tunnel syndrome (CTS). Electromyography is the best evaluation test to confirm the disease, as it shows a median reduced conduction velocity and/or conduction block; however, the usual CTS electrodiagnostic tests do not separate segmental demyelination alone from segmental demyelination plus secondary axonal degeneration. We studied 100 hands from CTS patients (classified as mild, moderate, and severe), and 50 hands from normal subjects. The median palmar sensory nerve action potential (SNAP) amplitude was measured and compared between the two groups. It would be expected that SNAP was normal if no axonal degeneration had occurred. The results showed that in mild CTS group and part of moderate CTS group SNAP amplitude was normal, whereas in severe CTS group, and part of moderate group SNAP amplitude was reduced, proving that axonal degeneration was involved. As it is well stated that axonal lesions have worse prognosis than segmental demyelinating ones, this simple test may help to preditic the CTS outcome and treatment
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Axones
/
Síndrome del Túnel Carpiano
/
Degeneración Nerviosa
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Arq. neuropsiquiatr
Asunto de la revista:
NEUROLOGIA
/
PSIQUIATRIA
Año:
2003
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil