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Efecto de la midodrina en la hipotensión sintomática en hemodiálisis / Effects of midodrine on orthostatic hypotension during hemodialysis
Cotera Farias, Alejandro; Alvo A., Miriam; Sanhueza V., María Eugenia; Elgueta S., Leticia; Gormaz B., Juan Pablo; Ibáñez B., Carlos; Cuadra C., Cristián.
Afiliación
  • Cotera Farias, Alejandro; Universidad de Chile. Hospital Clínico. Departamento de Medicina. CL
  • Alvo A., Miriam; Universidad de Chile. Hospital Clínico. Departamento de Medicina. CL
  • Sanhueza V., María Eugenia; Universidad de Chile. Hospital Clínico. Departamento de Medicina. CL
  • Elgueta S., Leticia; Universidad de Chile. Hospital Clínico. Departamento de Medicina. CL
  • Gormaz B., Juan Pablo; s.af
  • Ibáñez B., Carlos; s.af
  • Cuadra C., Cristián; s.af
Rev. méd. Chile ; 130(9): 1009-1013, sept. 2002. tab, graf
Article en Es | LILACS | ID: lil-323234
Biblioteca responsable: CL1.1
RESUMO

Background:

Hypotension occurs in 20 percent of hemodialysis procedures.

Aim:

To study the effects of midodrine on hypotension during hemodialysis. Patients and

methods:

Ten patients on chronic hemodialysis and with a history of hypotension during the procedure, were studied. They received midodrine 10 mg per os or placebo during 5 dialytic procedures each, in a double blind cross over design.

Results:

Blood pressure levels prior to dialysis were similar during the midodrine or placebo administration periods. During dialysis, systolic blood pressure fell 19.3ñ28 mmHg with midodrine and 23.4ñ28 mmHg with placebo. Diastolic blood pressure fell 7.3ñ11.5 mmHg with midodrine and 11.1ñ12 mmHg with placebo. The reduction in median arterial pressure was also less pronounced with midodrine.

Conclusions:

Midodrine lessens the fall in arterial pressure during hemodialysis, in patients with symptomatic hypotension
Asunto(s)
Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Hipotensión / Midodrina Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Female / Humans / Male Idioma: Es Revista: Rev. méd. Chile Asunto de la revista: MEDICINA Año: 2002 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Chile
Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Hipotensión / Midodrina Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Female / Humans / Male Idioma: Es Revista: Rev. méd. Chile Asunto de la revista: MEDICINA Año: 2002 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Chile