Tumores neuroendocrinos gástricos: presentación clínica, endoscópica y alternativas de tratamiento / Clinical and endoscopic presentation of gastric neuroendocrine tumors
Rev. méd. Chile
; 130(9): 985-992, sept. 2002. ilus, tab
Article
en Es
| LILACS
| ID: lil-323231
Biblioteca responsable:
CL1.1
ABSTRACT
Background:
Gastric neuroendocrine tumors correspond to less than 1 percent of all gastric tumors. These tumors can be of three types. Seventy five percent are type I and are associated to chronic atrophic gastritis type A (CAG- A). Half of them are associated with pernicious anemia. Type II tumors are associated with Zollinger Ellison syndrome and type I multiple endocrine neoplasia. Type III are sporadic tumors.Aim:
To report the clinical, endoscopical features and response to the treatment of gastric neuroendocrine tumors. Patients andmethods:
A retrospective study of eleven patients (seven male, aged 38 to 72 years old) with a pathological diagnosis of gastric neuroendocrine tumor. Their clinical presentation, associated diseases, treatment and follow up were reviewed.Results:
Epigastric pain was present in eight patients, weight loss in three, epigastric pain and weight loss in one and post prandial abdominal pain in two. At endoscopy, multiple polyps in the fundus were observed in six, verrucose gastritis in one, polyps in the antrum in one, two subcardial polyps in 1, a fundus ulcer in one and a Bormann III type lesion in one. Chronic atrophic gastritis was diagnosed in seven patients and pernicious anemia in five. Serum gastrin levels were determined in 4 patients and were high in all. Four subjects were treated with endoscopic polipectomy only. A partial or total gastrectomy was done in seven patients. No complications or mortality occurred during the follow up.Conclusions:
Abdominal pain is a common presentation of patients with gastric neuroendocrine neoplasia. Polyps predominantly in the fundus are the most common endoscopic finding. Surgical treatment or endoscopical polypectomy, depending of the extension of the disease, yield satisfactoryresults:
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Neoplasias Gástricas
/
Tumores Neuroendocrinos
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2002
Tipo del documento:
Article
País de afiliación:
Chile
Pais de publicación:
Chile