Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;31(11): 1443-8, Nov. 1998. tab, graf
Article
en En
| LILACS
| ID: lil-224480
Biblioteca responsable:
BR1.1
ABSTRACT
We investigated whether chronic stress applied from prepuberty to full sexual maturity interferes with spermatogenic and androgenic testicular functions. Male Wistar rats (40 days old) were immobilized 6 h a day for 60 days. Following immobilization, plasma concentrations of corticosterone and prolactin increased 135 per cent and 48 per cent, respectively, while plasma luteinizing hormone and testosterone presented a significant decrease of 29 per cent and 37 per cent, respectively. Plasma concentration of follicle-stimulating hormone was not altered in stressed rats. Chronic stress reduced the amount of mature spermatids in the testis by 16 per cent and the spermatozoon concentration in the cauda epididymidis by 32 per cent. A 17 per cent reduction in weight and a 42 per cent decrease in DNA content were observed in the seminal vesicle of immobilized rats but not in its fructose content. The growth and secretory activity of the ventral prostate were not altered by chronic stress.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Maduración Sexual
/
Espermatogénesis
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Estrés Fisiológico
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Testículo
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Hormonas
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Inmovilización
Límite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
/
Rev. bras. pesqui. méd. biol
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
1998
Tipo del documento:
Article
/
Project document
Pais de publicación:
Brasil