Structural features of LPPG and related compounds isolated from Trypanosoma cruzi trypomastigotes
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;27(2): 227-31, Feb. 1994. ilus
Article
en En
| LILACS
| ID: lil-138289
Biblioteca responsable:
BR26.1
RESUMO
A hydrophobic fraction isolated from trypomastigotes of Trypanosoma cruzi is being characterized using immunological and chemical techniques. The lipopeptidophosphoglycan (LPPG) was identified in this fraction since it gave a positive reaction with anti-LPPG rabbit serum and had similar structural features such as the presence of ceramide as the lipid moiety, furanoic galactose, and a glycan moiety consistent with that obtained from an authentic sample of epimastigote LPPG, as judged by thin-layer chromatography. Furthermore, the hydrophobic fraction contained other glycolipids with different structural features. The lipid moiety of these compounds is alkylglycerol rather than a ceramide, the carbohydrate chain appears to be less complex than that in LPPG and no reactivity was observed towards an anti-LPPG serum
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Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Fosfolípidos
/
Trypanosoma cruzi
/
Glicoconjugados
/
Peptidoglicano
Límite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
/
Rev. bras. pesqui. méd. biol
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
1994
Tipo del documento:
Article
/
Congress and conference
Pais de publicación:
Brasil