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Assessing the determination of salivary electrolytes and anti-Roand anti-La antibodies for the diagnosis of Sjögren’s Syndrome (SS)
Busamia, Beatriz; Linares, Jorge; Mazzeo, Marcelo; Finkelberg, Ana; Demarchi, Marcela; Gobbi, Carla; Albiero, Eduardo; Gonzales-Moles, Miguel-Angel.
Afiliación
  • Busamia, Beatriz; National University of Cordoba. Faculty of Dentistry. Cordoba. Argentina
  • Linares, Jorge; National University of Cordoba. Faculty of Dentistry. Cordoba. Argentina
  • Mazzeo, Marcelo; National University of Cordoba. Faculty of Dentistry. Cordoba. Argentina
  • Finkelberg, Ana; National University of Cordoba. Faculty of Dentistry. Cordoba. Argentina
  • Demarchi, Marcela; Hospital Córdoba - Sanatorium Allende. Rheumatology Service. Córdoba. Argentina
  • Gobbi, Carla; Hospital Córdoba - Sanatorium Allende. Rheumatology Service. Córdoba. Argentina
  • Albiero, Eduardo; Hospital Córdoba - Sanatorium Allende. Rheumatology Service. Córdoba. Argentina
  • Gonzales-Moles, Miguel-Angel; University of Granada. Department of Stomatology. Granada. Argentina
Med. oral patol. oral cir. bucal (Internet) ; Med. oral patol. oral cir. bucal (Ed.impr.);15(3): e437-e440, mayo 2010. tab
Article en En | IBECS | ID: ibc-84689
Biblioteca responsable: ES1.1
Ubicación: BNCS
ABSTRACT
The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence ofanti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosisof SS.Study design: 73 patients were studied, divided into the following experimental groups: primary Sjögren syndrome(SSp) (n=15), secondary SS (SSs) (n=17), dry mouth, dry eye without Sjögren’s syndrome (BO) (n=20)and healthy controls (C) (n=21). We conducted a baseline assessment of salivary flow and saliva sampling for themeasurement of sodium, chlorine, potassium, calcium and phosphate electrolytes, and the determination of anti-Ro/SSA and La/SSB antibodies; a serum sampling was made to assess antibody positivity.Results: Salivary flow in SSp, SSs and BO was significantly lower (p<0.001) relative to C. The salivary compositionof SS showed an increase of inorganic components. Anti-Ro/SSA and anti-La/SSB antibodies occurred morefrequently in serum and saliva in SS patients compared with BO and C, with higher frequency of positivity inserum compared with saliva.Conclusion: Our results suggest new tools that could aid the non-traumatic diagnosis of the origin of hyposalivation (AU)
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Saliva / Síndrome de Sjögren / Anticuerpos Antinucleares / Electrólitos Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Male Idioma: En Revista: Med. oral patol. oral cir. bucal (Ed.impr.) / Med. oral patol. oral cir. bucal (Internet) Año: 2010 Tipo del documento: Article
Buscar en Google
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Saliva / Síndrome de Sjögren / Anticuerpos Antinucleares / Electrólitos Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Male Idioma: En Revista: Med. oral patol. oral cir. bucal (Ed.impr.) / Med. oral patol. oral cir. bucal (Internet) Año: 2010 Tipo del documento: Article