Accidentes cerebrovasculares intrahospitalarios: perfil clínico y expectativas terapéuticas / The cost of neurological disease
Neurología (Barc., Ed. impr.)
; 23(1): 4-9, ene.-feb. 2008. ilus, tab
Article
en Es
| IBECS
| ID: ibc-63202
Biblioteca responsable:
ES15.1
Ubicación: ES15.1 - BNCS
Introducción. Los ictus intrahospitalarios han sido poco descritos. Son una oportunidad única para acortar los intervalos de trombólisis. Nos proponemos: a) describir sus rasgos clínicos y de valoración neurológica, y b) analizar en un hospital general terciario los casos potenciales y las exclusiones de fibrinólisis, justamente antes de su aprobación e implementación en el centro. Métodos. Casos recogidos de modo retrospectivo entre mayo de 2001 y mayo de 2004, identificados desde el archivo del hospital (CIE-9: 430-439; GRD: 14, 15, 16, 17, 532, 810) y a partir de interconsultas del servicio de neurología. Incluimos: a) procedencia y diagnóstico; b) mecanismo (Trial of Org 10172 in Acute Stroke Treatment, TOAST) y síndrome clínico (Escala Oxfordshire Community Stroke Project, OCSP); c) factores de riesgo vascular y enfermedad arterioesclerótica sintomática previa (EASP), y d) pronóstico, situación funcional al alta (escala de Rankin modificada, mRS) e intervalos de evaluación neurológica. Cada caso fue valorado según criterios SIST-MOST (registro europeo para monitorizar la seguridad del tratamiento trombolítico en el ictus-SIST-MOST) para tratamiento trombolítico. Resultados. Incluimos 183 casos (26 TIA, 149 ictus isquémicos y 5 hemorragias). Edad media: 70,1 años; 25%, >80 años. La procedencia más frecuente fue cardiología y servicios afines (31,8%), seguida de medicina interna (18%). El mecanismo dominante fue el cardioembólico (40 %). En 18 casos (11,77 %) fueron yatrogénicos. El 55,8 % habían sufrido EASP (ictus: 41; cardiopatía isquémica: 31). La mortalidad alcanzó el 33%. El 36% puntuaron ≥ 3 en la mRS al alta. Se solicitó valoración neurológica en el 89 %; en el 25% se hizo como urgente. De 149 ictus isquémicos, 5 casos (3,2%) eran candidatos potenciales a trombólisis. La cirugía invasiva, edad mayor de 80 años, enfermedades agudas graves o combinaciones fueron los factores de exclusión más frecuentes. Conclusiones. Los ictus intrahospitalarios son especialmente prevalentes en pacientes con EASP. Tienen mal pronóstico. El 3,2 % pueden ser tratados con fibrinólisis, aunque se requiere una mejor percepción de la urgencia y de los tiempos entre el personal hospitalario
Introduction. In-hospital strokes have been poorly reported. They provide an opportunity to shorten intervals for thrombolysis. Our proposals were: a) to describe their clinical features and neurological assesment, and b) regarding thrombolysis, to analyze potential candidates and exclusions at a general tertiary hospital, just before its approval/implementation at the center. Methods. Cases were retrospectively recruited between May 2001-May 2004. They were identified from discharching diagnosis (ICD-9: 430-439; GRD: 14, 15, 16, 17, 532, 810) and from consultations required to the neurology service. Data collected were: a) admitting diagnosis and service; b) mechanism of stroke (Trial of Org 10172 in Acute Stroke Treatment, TOAST) and clinical syndrome (Oxfordshire Community Stroke Project, OCSP); c) vascular risk factors and previous symptomatic artherioesclerotic disease (PSAD), and d) prognosis, functional status at discharge (mRankin scale, mRS) and timing for neurological assesment. Every case was considered regarding thrombolytic treatment accoding to Safe Implementation of Trombolysis in Stroke-Monitoring Study (SIST-MOST) criteria. Potential criteria for exclusion were registered. Results. 183 cases were included (26 transient ischemic accident, 149 ischemic strokes, 5 haemorrhages). Mean age: 74.5 years, 25.5 %, above 80 years. Main sources of patients were cardiology plus related services (31.8%) and internal medicine (18%). Dominant mecha-nism was cardioembolism (40%). 18 cases (11.77%) were yatrogenic. 55.8% had had PSAD (stroke: 41; ischemic cardiopahty: 31). Mortality reached 33%. 36% were discharged pointing 3 or above in the mRS. Expert neurological assesment was requested in 89%, but just for 25% it was considered an emergency. From 149 ischemic strokes, 5 cases (3.2 %) were potential candidates for thrombolysis. Mayor surgery, ageing (>80 years), severe acute disorders or combinations of them precluded thrombolysis. Conclusions. In-hospital strokes are particularly prevalent in patients with PSAD. Prognosis is poor. In 3.2% thrombolysis could be administered. To make this possible, a right perception of the timing and emergency should be encouraged among hospital staff
Introduction. In-hospital strokes have been poorly reported. They provide an opportunity to shorten intervals for thrombolysis. Our proposals were: a) to describe their clinical features and neurological assesment, and b) regarding thrombolysis, to analyze potential candidates and exclusions at a general tertiary hospital, just before its approval/implementation at the center. Methods. Cases were retrospectively recruited between May 2001-May 2004. They were identified from discharching diagnosis (ICD-9: 430-439; GRD: 14, 15, 16, 17, 532, 810) and from consultations required to the neurology service. Data collected were: a) admitting diagnosis and service; b) mechanism of stroke (Trial of Org 10172 in Acute Stroke Treatment, TOAST) and clinical syndrome (Oxfordshire Community Stroke Project, OCSP); c) vascular risk factors and previous symptomatic artherioesclerotic disease (PSAD), and d) prognosis, functional status at discharge (mRankin scale, mRS) and timing for neurological assesment. Every case was considered regarding thrombolytic treatment accoding to Safe Implementation of Trombolysis in Stroke-Monitoring Study (SIST-MOST) criteria. Potential criteria for exclusion were registered. Results. 183 cases were included (26 transient ischemic accident, 149 ischemic strokes, 5 haemorrhages). Mean age: 74.5 years, 25.5 %, above 80 years. Main sources of patients were cardiology plus related services (31.8%) and internal medicine (18%). Dominant mecha-nism was cardioembolism (40%). 18 cases (11.77%) were yatrogenic. 55.8% had had PSAD (stroke: 41; ischemic cardiopahty: 31). Mortality reached 33%. 36% were discharged pointing 3 or above in the mRS. Expert neurological assesment was requested in 89%, but just for 25% it was considered an emergency. From 149 ischemic strokes, 5 cases (3.2 %) were potential candidates for thrombolysis. Mayor surgery, ageing (>80 years), severe acute disorders or combinations of them precluded thrombolysis. Conclusions. In-hospital strokes are particularly prevalent in patients with PSAD. Prognosis is poor. In 3.2% thrombolysis could be administered. To make this possible, a right perception of the timing and emergency should be encouraged among hospital staff
Buscar en Google
Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Accidente Cerebrovascular
Tipo de estudio:
Health_economic_evaluation
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
Es
Revista:
Neurología (Barc., Ed. impr.)
Año:
2008
Tipo del documento:
Article