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Actinic cheilitis: Proposal of a clinical index
Medeiros, Cristianne Kalinne Santos; Lopes, Maria Luiza Diniz de Sousa; Silveira, Éricka Janine Dantas da; Lima, Kenio Costa; Oliveira, Patrícia Teixeira de.
Afiliación
  • Medeiros, Cristianne Kalinne Santos; Federal University of Rio Grandedo Norte. Department of Dentistry. Natal. Brazil
  • Lopes, Maria Luiza Diniz de Sousa; Federal University of Rio Grandedo Norte. Department of Dentistry. Natal. Brazil
  • Silveira, Éricka Janine Dantas da; Federal University of Rio Grandedo Norte. Department of Dentistry. Natal. Brazil
  • Lima, Kenio Costa; Federal University of Rio Grandedo Norte. Department of Dentistry. Natal. Brazil
  • Oliveira, Patrícia Teixeira de; Federal University of Rio Grandedo Norte. Department of Dentistry. Natal. Brazil
Med. oral patol. oral cir. bucal (Internet) ; Med. oral patol. oral cir. bucal (Ed.impr.);27(4): 1-9, July 2022. tab, graf, ilus
Article en En | IBECS | ID: ibc-209794
Biblioteca responsable: ES1.1
Ubicación: ES15.1 - BNCS
ABSTRACT
Background: Actinic cheilitis is a potentially malignant lesion most commonly found in the lower lip of individuals with chronic exposure to ultraviolet radiation. The aim of this study was to develop and to test a clinical indexthat can be used to assess the severity of actinic cheilitis.Material and Methods: The clinical index of actinic cheilitis was applied to 36 patients. An incisional biopsy wasobtained to grade oral epithelial dysplasias following the World Health Organization (WHO) and binary systems,and to evaluate their association with clinical characteristics by Fisher’s exact test (P<0.05). The accuracy of theindex was evaluated based on sensitivity, specificity, positive and negative predictive values, and receiver operating curve.Results: The blurring between the border of the lip and the skin was significantly associated with cases withoutdysplasia/mild epithelial dysplasia (P=0.041) and with low risk of malignancy (P=0.005). Ulcers and crusts weresignificantly associated with moderate/severe epithelial dysplasia (P=0.002 and P=0.012, respectively) and highrisk of malignancy (P=0.005 and P=0.045, respectively). Erosion showed a significant association only with highrisk cases of malignancy (P=0.024). The cut-off values of the diagnostic test showing the best performance were10 for the WHO grading system and 11 for the binary system.Conclusions: The index cut-offs with the highest accuracy were considered indicators for a biopsy. Erosion, ulceration and crusts were associated with more severe oral epithelial dysplasias. (AU)
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Texto completo: 1 Colección: 06-national / ES Base de datos: IBECS Asunto principal: Rayos Ultravioleta / Neoplasias de los Labios / Queilitis / Hiperplasia / Labio Límite: Humans Idioma: En Revista: Med. oral patol. oral cir. bucal (Ed.impr.) / Med. oral patol. oral cir. bucal (Internet) Año: 2022 Tipo del documento: Article
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Texto completo: 1 Colección: 06-national / ES Base de datos: IBECS Asunto principal: Rayos Ultravioleta / Neoplasias de los Labios / Queilitis / Hiperplasia / Labio Límite: Humans Idioma: En Revista: Med. oral patol. oral cir. bucal (Ed.impr.) / Med. oral patol. oral cir. bucal (Internet) Año: 2022 Tipo del documento: Article