Your browser doesn't support javascript.
loading
Epidemiology and survival outcomes of lip, oral cavity, and oropharyngeal squamous cell carcinoma in a southeast Brazilian population
Louredo, Brendo Vinícius Rodrigues; Vargas, Pablo Agustin; Pérez-de-Oliveira, Maria Eduarda; Lopes, Márcio Ajudarte; Kowalski, Luiz Paulo; Curado, Maria Paula.
Afiliación
  • Louredo, Brendo Vinícius Rodrigues; State University of Campinas (UNICAMP). Piracicaba Dental School. Piracicaba. Brazil
  • Vargas, Pablo Agustin; State University of Campinas (UNICAMP). Piracicaba Dental School. Piracicaba. Brazil
  • Pérez-de-Oliveira, Maria Eduarda; State University of Campinas (UNICAMP). Piracicaba Dental School. Piracicaba. Brazil
  • Lopes, Márcio Ajudarte; State University of Campinas (UNICAMP). Piracicaba Dental School. Piracicaba. Brazil
  • Kowalski, Luiz Paulo; University of São Paulo (USP). School of Medicine. São Paulo. Brazil
  • Curado, Maria Paula; A. C. Camargo Cancer Center (ACCCC). Group of Epidemiology and Statistics on Cancer. São Paulo. Brazil
Med. oral patol. oral cir. bucal (Internet) ; 27(3): e274-e284, may. 2022. ilus, graf, tab
Article en En | IBECS | ID: ibc-204656
Biblioteca responsable: ES1.1
Ubicación: ES15.1 - BNCS
ABSTRACT
Background: Lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC) represent a major health problem in the global scenario. In South America, the highest incidence rates are seen in Brazil. Therefore, the epidemiological and clinical profile and survival outcomes of lip, oral cavity, and oropharyngeal SCC was studied in São Paulo State, Brazil. Material and Methods: The clinicopathological data of 12,099 patients with lip, oral cavity, and oropharyngeal SCC were obtained from hospital cancer registries of the Fundação Oncocentro de São Paulo, Brazil (2010–2015). Survival rates and other analyses were performed using SPSS software. Results: A clear male predominance was observed, particularly for patients with oropharyngeal SCC (88.3%). The average age of patients was higher for lip cases (65 ± 13.5 years) compared to other sites. The schooling level was low for most patients, especially in lip cases (87.9%). Most of the patients with oral cavity (71.8%) and oropharyngeal (86.3%) SCC had advanced-stage (III–IV) disease. However, the majority of lip cases (83.3%) were at an early stage (I–II). Surgical excision was the main treatment for lip (72%) and oral cavity SCC (23.5%), and chemoradiotherapy was the main treatment for oropharyngeal SCC (40.2%). The 5-year overall survival (OS) for patients with lip, oral cavity, and oropharyngeal SCC were 66.3, 30.9, and 22.6%, respectively. Multivariate analysis revealed that the determinants of OS were different for lip, oral cavity, and oropharyngeal SCC, except for those at the clinical stage, which was an independent predictor for all sites. Conclusions: OS-independent determinants varied according to the affected site. Oral cavity and oropharyngeal SCC presented worse survival rates than those for lip SCC.(AU)
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
Buscar en Google

Texto completo: 1 Colección: 06-national / ES Base de datos: IBECS Asunto principal: Neoplasias de la Boca / Neoplasias Orofaríngeas / Carcinoma de Células Escamosas de Cabeza y Cuello / Neoplasias de Cabeza y Cuello / Labio Límite: Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Med. oral patol. oral cir. bucal (Internet) Año: 2022 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
Imprimir
XML
Buscar en Google

Texto completo: 1 Colección: 06-national / ES Base de datos: IBECS Asunto principal: Neoplasias de la Boca / Neoplasias Orofaríngeas / Carcinoma de Células Escamosas de Cabeza y Cuello / Neoplasias de Cabeza y Cuello / Labio Límite: Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Med. oral patol. oral cir. bucal (Internet) Año: 2022 Tipo del documento: Article