Endoscopic ultrasound (EUS) guided fine needle biopsy (FNB) with the Procore(TM) needle provides inadequate material for the histological diagnosis of early chronic pancreatitis
Rev. esp. enferm. dig
; 110(8): 510-514, ago. 2018. ilus, tab
Article
en En
| IBECS
| ID: ibc-177761
Biblioteca responsable:
ES1.1
Ubicación: BNCS
ABSTRACT
Background: diagnosis of early chronic pancreatitis (CP) is hampered due to the low accuracy of current imaging techniques and the absence of methods for histological confirmation. We aimed to evaluate the efficacy of endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for the histological diagnosis of early CP. Methods: a prospective, cross-sectional, single-center study was designed. Consecutive patients referred for EUS with a clinical suspicion of CP were evaluated for inclusion into the study. Inclusion criteria were age > 18 years and indeterminate EUS findings for the diagnosis of CP according to the Rosemont classification. EUS-FNB of the body of the pancreas was performed with Procore(TM) needles. Tissue samples were immersed into a methanol-based buffered preservative solution for cytohistological evaluation. The quality of the samples obtained and the histological findings were evaluated. Procedure-related complications were recorded. Results: the study was stopped after eleven patients were included due to safety concerns and poor diagnostic yield. The mean age of the patients was 50.3 years (range 33-70 years) and six were male. Samples were of poor quality in five cases, but were sufficient for cell-block evaluation. An inflammatory infiltration with mild fibrosis was identified in two cases and neither inflammatory infiltration nor fibrosis was identified in three cases. With regard to the other six cases, isolated inflammatory cells were observed in one case, although the cellularity was poor and unsuitable for cytological evaluation in five cases. There was one major complication (9.1%) of acute pancreatitis that required hospitalization for 48 hours. Conclusion: EUS-FNB is technically feasible in patients with EUS findings categorized as indeterminate for a CP diagnosis. However, the diagnostic yield is poor and there is a non-negligible risk of complications
RESUMEN
No disponible
Texto completo:
1
Colección:
06-national
/
ES
Base de datos:
IBECS
Asunto principal:
Técnicas Histológicas
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Pancreatitis Crónica
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Biopsia por Aspiración con Aguja Fina Guiada por Ultrasonido Endoscópico
Límite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Rev. esp. enferm. dig
Año:
2018
Tipo del documento:
Article