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Genomic Plasticity of Vibrio cholerae
Escudero, Jose Antonio; Mazel, Didier.
Afiliación
  • Escudero, Jose Antonio; Universidad Complutense Madrid. Health Surveillance Centre. Madrid. Spain
  • Mazel, Didier; Universidad Complutense de Madrid. Facultad de Veterinaria. Departamento de Sanidad Animal. Madrid. Spain
Int. microbiol ; 20(3): 138-148, sept. 2017. ilus
Article en En | IBECS | ID: ibc-171332
Biblioteca responsable: ES1.1
Ubicación: BNCS
ABSTRACT
Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that still today causes 95.000 deaths worldwide every year. V. cholerae is a free living marine organism that interacts with and infects a variety of organisms, from amoeba to humans, including insects and crustaceans. The complexity of the lifestyle and ecology of V. cholerae suggests a high genetic and phenotypic plasticity. In this review, we will focus on two peculiar genomic features that enhance genetic plasticity in this bacterium: the division of its genome in two different chromosomes and the presence of the superintegron, a gene capture device that acts as a large, low-cost memory of adaptive functions, allowing V. cholerae to adapt rapidly (AU)
RESUMEN
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Asunto(s)

Texto completo: 1 Colección: 06-national / ES Base de datos: IBECS Asunto principal: Vibrio cholerae / Cólera / Factores Procarióticos de Iniciación / Diarrea Tipo de estudio: Etiology_studies Límite: Female / Humans / Male Idioma: En Revista: Int. microbiol Año: 2017 Tipo del documento: Article

Texto completo: 1 Colección: 06-national / ES Base de datos: IBECS Asunto principal: Vibrio cholerae / Cólera / Factores Procarióticos de Iniciación / Diarrea Tipo de estudio: Etiology_studies Límite: Female / Humans / Male Idioma: En Revista: Int. microbiol Año: 2017 Tipo del documento: Article