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A comparison of two clinical scores for bronchiolitis. A multicentre and prospective study conducted in hospitalised infants
Rivas-Juesas, C; Rius Peris, JM; García, AL; Madramany, AA; Peris, MG; Álvarez, LV; Primo, J.
Afiliación
  • Rivas-Juesas, C; Hospital de Sagunto. Valencia. Spain
  • Rius Peris, JM; Hospital Virgen de la Luz. Valencia. Spain
  • García, AL; Hospital de Sagunto. Valencia. Spain
  • Madramany, AA; Hospital de Sagunto. Valencia. Spain
  • Peris, MG; Hospital LLuis Alcanyís. Spain
  • Álvarez, LV; Hospital de Vinaroz. Castellón. Spain
  • Primo, J; Hospital de Sagunto. Valencia. Spain
Allergol. immunopatol ; 46(1): 15-23, ene.-feb. 2018. tab, graf
Article en En | IBECS | ID: ibc-170783
Biblioteca responsable: ES1.1
Ubicación: BNCS
ABSTRACT
Background: There are a number of clinical scores for bronchiolitis but none of them are firmly recommended in the guidelines. Method: We designed a study to compare two scales of bronchiolitis (ESBA and Wood Downes Ferres) and determine which of them better predicts the severity. A multicentre prospective study with patients <12 months with acute bronchiolitis was conducted. Each patient was assessed with the two scales when admission was decided. We created a new variable "severe condition" to determine whether one scale afforded better discrimination of severity. A diagnostic test analysis of sensitivity and specificity was made, with a comparison of the AUC. Based on the optimum cut-off points of the ROC curves for classifying bronchiolitis as severe we calculated new Se, Sp, LR+ and LR- for each scale in our sample. Results: 201 patients were included, 66.7% males and median age 2.3 months (IQR = 1.3-4.4). Thirteen patients suffered bronchiolitis considered to be severe, according to the variable severe condition. ESBA showed a Se = 3.6%, Sp = 98.1%, and WDF showed Se = 46.2% and Sp = 91.5%. The difference between the two AUC for each scale was 0.02 (95%CI: 0.01-0.15), p = 0.72. With new cut-off points we could increase Se and Sp for ESBA: Se=84.6%, Sp = 78.7%, and WDF showed Se = 92.3% and Sp = 54.8%; with higher LR. Conclusions: None of the scales studied was considered optimum for assessing our patients. With new cut-off points, the scales increased the ability to classify severe infants. New validation studies are needed to prove these new cut-off points (AU)
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Bronquiolitis Tipo de estudio: Clinical_trials / Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: Allergol. immunopatol Año: 2018 Tipo del documento: Article
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Bronquiolitis Tipo de estudio: Clinical_trials / Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Child / Humans Idioma: En Revista: Allergol. immunopatol Año: 2018 Tipo del documento: Article