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Initial experience in sentinel lymph node detection in pancreatic cancer / Experiencia inicial en la detección del ganglio centinela en cáncer de páncreas
Beisani, M; Roca, I; Cardenas, R; Blanco, L; Abu-Suboh, M; Dot, J; Armengol, JR; Olsina, JJ; Balsells, J; Charco, R; Castell, J.
Afiliación
  • Beisani, M; Department of HPB Surgery. Hospital Vall d’Hebron. Department of HPB Surgery. Barcelona. Spain
  • Roca, I; Autonomous University of Barcelona. Hospital Vall d’Hebron. Department of Nuclear Medicine. Barcelona. Spain
  • Cardenas, R; Autonomous University of Barcelona. Hospital Vall d’Hebron. Department of Nuclear Medicine. Barcelona. Spain
  • Blanco, L; Department of HPB Surgery. Hospital Vall d’Hebron. Department of HPB Surgery. Barcelona. Spain
  • Abu-Suboh, M; Autonomous University of Barcelona. Hospital Vall d’Hebron. Department of Digestive Endoscopy. Barcelona. Spain
  • Dot, J; Autonomous University of Barcelona. Hospital Vall d’Hebron. Department of Digestive Endoscopy. Barcelona. Spain
  • Armengol, JR; Autonomous University of Barcelona. Hospital Vall d’Hebron. Department of Digestive Endoscopy. Barcelona. Spain
  • Olsina, JJ; University of Lleida. Hospital Arnau de Vilanova. Department of Surgery. Lleida. Spain
  • Balsells, J; Department of HPB Surgery. Hospital Vall d’Hebron. Department of HPB Surgery. Barcelona. Spain
  • Charco, R; Department of HPB Surgery. Hospital Vall d’Hebron. Department of HPB Surgery. Barcelona. Spain
  • Castell, J; Autonomous University of Barcelona. Hospital Vall d’Hebron. Department of Nuclear Medicine. Barcelona. Spain
Rev. esp. med. nucl. imagen mol. (Ed. impr.) ; 35(5): 287-291, sept.-oct. 2016. tab, ilus, graf
Article en En | IBECS | ID: ibc-155011
Biblioteca responsable: ES1.1
Ubicación: BNCS
ABSTRACT
Background. The local recurrence of pancreatic cancer is around 30% when complete resection can be achieved. Extended lymphatic resections may improve survival, but increases severe morbidity. As accurate patient selection should be mandatory, a new method is presented for pancreatic sentinel lymph node (SLN) detection with lymphoscintigraphy and gamma probe. Materials and methods. Seven patients with cT2N0M0 pancreatic head cancer were enrolled between 2009 and 2012 in this prospective study. One day prior to surgery, preoperative lymphoscintigraphy with echoendoscopic intratumoural administration of Tc99m-labelled nanocolloid was performed, with planar and SPECT-CT images obtained 2h later. Gamma probe detection of SLN was also carried out during surgery. Results. Radiotracer administration was feasible in all patients. Scintigraphy images showed inter-aortocaval lymph nodes in 2 patients, hepatoduodenal ligament lymph nodes in 1, intravascular injection in 3, intestinal transit in 5, and main pancreatic duct visualisation in 1. Surgical resection could only be achieved in 4 patients owing to locally advanced disease. Intraoperative SLN detection was accomplished in 2 patients, both with negative results. Only in one patient could SLN be confirmed as truly negative by final histopathological analysis. Conclusions. This new method of pancreatic SLN detection is technically feasible, but challenging. Our preliminary results with 7 patients are not sufficient for clinical validation (AU)
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Neoplasias Pancreáticas / Tomografía Computarizada de Emisión de Fotón Único / Técnicas de Sonda Molecular / Biopsia del Ganglio Linfático Centinela / Linfocintigrafia Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Rev. esp. med. nucl. imagen mol. (Ed. impr.) Año: 2016 Tipo del documento: Article
Buscar en Google
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Neoplasias Pancreáticas / Tomografía Computarizada de Emisión de Fotón Único / Técnicas de Sonda Molecular / Biopsia del Ganglio Linfático Centinela / Linfocintigrafia Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Female / Humans / Male Idioma: En Revista: Rev. esp. med. nucl. imagen mol. (Ed. impr.) Año: 2016 Tipo del documento: Article