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Lung adenocarcinoma in the era of targeted therapies: histological classification, sample priorization, and predictive biomarkers
Conde, E; Angulo, B; Izquierdo, E; Paz-Ares, L; Belda-Iniesta, C; Hidalgo, M; López-Ríos, F.
Afiliación
  • Conde, E; Universidad San Pablo-CEU. Hospital Universitario Madrid Sanchinarro. Centro Integral Oncológico Clara Campal. Madrid. Spain
  • Angulo, B; Universidad San Pablo-CEU. Hospital Universitario Madrid Sanchinarro. Centro Integral Oncológico Clara Campal. Madrid. Spain
  • Izquierdo, E; Universidad San Pablo-CEU. Hospital Universitario Madrid Sanchinarro. Centro Integral Oncológico Clara Campal. Madrid. Spain
  • Paz-Ares, L; Hospital Universitario Virgen del Rocío. Instituto de Biomedicina de Sevilla (IBIS). Sevilla. Spain
  • Belda-Iniesta, C; Universidad San Pablo-CEU. Hospital Universitario Madrid Sanchinarro. Centro Integral Oncológico Clara Campal. Madrid. Spain
  • Hidalgo, M; Universidad San Pablo-CEU. Hospital Universitario Madrid Sanchinarro. Centro Integral Oncológico Clara Campal. Madrid. Spain
  • López-Ríos, F; Universidad San Pablo-CEU. Hospital Universitario Madrid Sanchinarro. Centro Integral Oncológico Clara Campal. Madrid. Spain
Clin. transl. oncol. (Print) ; 15(7): 503-508, jul. 2013. ilus
Article en En | IBECS | ID: ibc-127462
Biblioteca responsable: ES1.1
Ubicación: BNCS
ABSTRACT
The arrival of targeted therapies has presented both a conceptual and a practical challenge in the treatment of patients with advanced non-small cell lung carcinomas (NSCLCs). The relationship of these treatments with specific histologies and predictive biomarkers has made the handling of biopsies the key factor for success. In this study, we highlight the balance between precise histological diagnosis and the practice of conducting multiple predictive assays simultaneously. This can only be achieved where there is a commitment to multidisciplinary working by the tumor board to ensure that a sensible protocol is applied. This proposal for prioritizing samples includes both recent technological advances and the some of the latest discoveries in the molecular classification of NSCLCs (AU)
Asunto(s)
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Colección: 06-national / ES Base de datos: IBECS Asunto principal: Adenocarcinoma / Biomarcadores de Tumor / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Clin. transl. oncol. (Print) Año: 2013 Tipo del documento: Article
Buscar en Google
Colección: 06-national / ES Base de datos: IBECS Asunto principal: Adenocarcinoma / Biomarcadores de Tumor / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Clin. transl. oncol. (Print) Año: 2013 Tipo del documento: Article