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Acute effect of the gastrokinetics cisapride and metoclopramide on the gastric emptying function in patients with the early satiety syndrome.
Ghigliani, M; Iantorno, G; Vázquez, S; Varela, A.
Afiliación
  • Varela, A; Department of Gastroenterology, Hospital de Clinicas José de San Martín, Buenos Aires, Argentina..
Acta gastroenterol. latinoam ; 17(1): 43-50, 1987.
Article en En | BINACIS | ID: bin-52653
Biblioteca responsable: AR40.1
ABSTRACT
Ten patients with postprandial upper abdominal discomfort, 4 of them having delayed gastric emptying, were included in a single-blind y camera study aimed at comparing the effects of cisapride and metoclopramide on gastric emptying. The two drugs were given sequentially, at a one-week interval, at a single oral dose of 10 mg, 15 minutes before intake of a labelled ordinary test meal. Applying a power exponential mathematical model to the y-camera data, T1/2 and the shape of the emptying curve were determined. The median half-emptying time (T1/2) was reduced from 81.5 min. in the basal condition to 62.5 min (-23
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Colección: 06-national / AR Base de datos: BINACIS Tipo de estudio: Clinical_trials Idioma: En Revista: Acta gastroenterol. latinoam Año: 1987 Tipo del documento: Article Pais de publicación: Argentina
Buscar en Google
Colección: 06-national / AR Base de datos: BINACIS Tipo de estudio: Clinical_trials Idioma: En Revista: Acta gastroenterol. latinoam Año: 1987 Tipo del documento: Article Pais de publicación: Argentina