Synthesis and contents of pancreatic exportable enzymes. Effect of oleic acid intraduodenal administration.

Calvo, E L; Vaccaro, M I; Tumilasci, O R; Iovanna, J L

Calvo, E L; Vaccaro, M I; Tumilasci, O R; Iovanna, J L.

Afiliación

Iovanna, J L; Departamento de Fisiologia, Facultad de Medicina, Universidad de Buenos Aires, Argentina..

Acta Physiol. Pharmacol. Latinoam ; 38(2): 145-50, 1988.

Article en En | BINACIS | ID: bin-52383

Biblioteca responsable: AR1.1

ABSTRACT

ABSTRACT

The effect of intraduodenal oleic acid administration on protein synthesis and enzymatic levels in rat pancreas was investigated. Sprague-Dawley rats were sacrificed at 20, 40, 60, and 80 min after intraduodenal oleic acid administration. Ten minutes before sacrifice, the rats were injected with 50 microCi 3H-Phenylalanine intraperitoneally. Amylase (Am), chymotrypsinogen (Chtg), trypsinogen (Tg) and lipase (Li) activities, and 3H-Phenylalanine incorporation to total secretory proteins were determined in pancreas homogenates. Forty minutes after oleic acid administration, the activities of Chtg, Tg and Li were significantly increased (45, 38 and 23

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Colección: 06-national / AR Base de datos: BINACIS Idioma: En Revista: Acta Physiol. Pharmacol. Latinoam Año: 1988 Tipo del documento: Article Pais de publicación: Argentina

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