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Trypanosoma cruzi: inducción de alteraciones del sistema nervioso periférico en diferentes cepas de ratones. / [Trypanosoma cruzi: induction of changes in the peripheral nervous system in different strains of mice]
Sanz, O P; Cardoni, R L; Celentano, A M; Rimoldi, M T; Sica, R E; González Cappa, S M.
Afiliación
  • González Cappa, S M; División Neurología, Hospital Ramos Mejía, Buenos Aires, Argentina..
Rev. argent. microbiol ; 23(1): 30-4, 1991 Jan-Feb.
Article en Es | BINACIS | ID: bin-51360
Biblioteca responsable: AR32.1
ABSTRACT
This study has been designed to find an easy method to evaluate the motor unit alterations induced during experimental T. cruzi infections. Different mouse strains infected with three strains of T. cruzi were used to perform conventional needle electromyography, in one of the lower limb hamstring muscles; amplitude, duration and number of phases of single motor unit potentials were measured. The following parasite strain to mouse strain relationship was investigated, in mice inoculated intraperitoneally with bloodstream forms of T. cruzi Tulahuen and C3H/HeN, C57Bl, Balb/c, Swiss; CA-I and C3H/HeN, Rockland, NIH; RA and C3H/HeN, Rockland. T. cruzi-induced denervating alterations were found in both C3H/HeN and C57Bl mice infected with the Tulahuen strain, as well as in C3H/HeN mice inoculated with the CA-I strain. Moreover, CA-I trypomastigotes could produce primary muscle changes in C3H/HeN and NIH mice. The technique employed in this investigation proved to be an easy and adequate way to detect changes within the motor unit during T. cruzi infection in mice.
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Colección: 06-national / AR Base de datos: BINACIS Idioma: Es Revista: Rev. argent. microbiol Año: 1991 Tipo del documento: Article Pais de publicación: Argentina
Buscar en Google
Colección: 06-national / AR Base de datos: BINACIS Idioma: Es Revista: Rev. argent. microbiol Año: 1991 Tipo del documento: Article Pais de publicación: Argentina