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Pregnancy outcomes in young mothers with perinatally and behaviorally acquired HIV infections in Rio de Janeiro
Lundberg, Per; Andersson, Rune; Machado, Elizabeth S; Costa, Tomaz Pinheiro da; Hofer, Cristina Barroso.
Afiliación
  • Lundberg, Per; Gothenburg University. Sahlgrenska Academy. Institute of Biomedicine. Gothenburg. SE
  • Andersson, Rune; Gothenburg University. Sahlgrenska Academy. Institute of Biomedicine. Gothenburg. SE
  • Machado, Elizabeth S; Universidade Federal do Rio de Janeiro. Instituto de Puericultura e Pediatria Martagão Gesteira. Departmento de Medicina Preventiva. Rio de Janeiro. BR
  • Costa, Tomaz Pinheiro da; Universidade Federal do Rio de Janeiro. Instituto de Puericultura e Pediatria Martagão Gesteira. Departmento de Medicina Preventiva. Rio de Janeiro. BR
  • Hofer, Cristina Barroso; Universidade Federal do Rio de Janeiro. Instituto de Puericultura e Pediatria Martagão Gesteira. Departmento de Medicina Preventiva. Rio de Janeiro. BR
Braz. j. infect. dis ; 22(5): 412-417, Sept.-Oct. 2018. tab
Article en En | LILACS | ID: biblio-974234
Biblioteca responsable: BR1.1
ABSTRACT
ABSTRACT

Background:

Perinatally HIV-infected children are surviving into adulthood, and getting pregnant. There is a scarcity of information on health and pregnancy outcomes in these women.

Aim:

To evaluate characteristics related to HIV disease and pregnancy outcomes in perinatally infected women, and to compare these women with a group of youth with behaviorally acquired HIV-infection, at a reference hospital in Rio de Janeiro, Brazil.

Methods:

A cohort study. Epidemiological, clinical, and laboratory data were compared between perinatally (PHIV) and behaviorally HIV-infected (BHIV) pregnant youth with the primary aim to study pregnancy outcomes in the PHIV group and compare with outcomes to BHIV group.

Results:

Thirty-two pregnancies occurred in PHIV group, and 595 in BHIV group. A total of seven (22%) PHIV women and 64 (11%) BHIV women had a premature delivery (p = 0.04), however, when adjusting for younger age at pregnancy, and antiretroviral therapy initiation in 1st trimester of pregnancy (OR = 18.66, 95%CI = 5.52-63.14), the difference was no longer significant. No cases of mother-to-child HIV transmission (MTCT) were observed in the PHIV group while there was a 2% MTCT rate in BHIV group.

Conclusion:

Pregnancy among PHIV was as safe as among BHIV. The differences between those groups were probably related to treatment and prolonged care in the first group.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Complicaciones Infecciosas del Embarazo / Resultado del Embarazo / Infecciones por VIH Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Female / Humans / Pregnancy País/Región como asunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2018 Tipo del documento: Article País de afiliación: Brasil / Suecia Pais de publicación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Complicaciones Infecciosas del Embarazo / Resultado del Embarazo / Infecciones por VIH Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Female / Humans / Pregnancy País/Región como asunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2018 Tipo del documento: Article País de afiliación: Brasil / Suecia Pais de publicación: Brasil