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In vitro antitubercular activity of extract and constituents from the stem bark of Disthemonanthus benthamianus
Evina, Jean Noel; Bikobo, Dominique Serge Ngono; Zintchem, Auguste Abouem A.; Nyemeck II, Norbert Mbabi; Ndedi, Esther Del Florence Moni; Diboué, Patrick Hervé Betote; Nyegue, Maximilienne Ascension; Atchadé, Alex de Théodore; Pegnyemb, Dieudonné Emmanuel; Koert, Ulrich; Bochet, Christian G..
Afiliación
  • Evina, Jean Noel; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Bikobo, Dominique Serge Ngono; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Zintchem, Auguste Abouem A.; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Nyemeck II, Norbert Mbabi; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Ndedi, Esther Del Florence Moni; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Diboué, Patrick Hervé Betote; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Nyegue, Maximilienne Ascension; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Atchadé, Alex de Théodore; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Pegnyemb, Dieudonné Emmanuel; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Koert, Ulrich; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
  • Bochet, Christian G.; University of Yaoundé I. Faculty of Science. Department of Organic Chemistry. Yaoundé. CM
Rev. bras. farmacogn ; 27(6): 739-743, Nov.-Dec. 2017. tab, graf
Article en En | LILACS | ID: biblio-898732
Biblioteca responsable: BR8.1
ABSTRACT
ABSTRACT A new C-glycosylflavone, apigenin 7-methyl ether 6-C-[β-xylopyranosyl-(1→3)-β-glucopyranoside] named distemonanthoside was isolated from the stem bark of Distemonanthus benthamianus Baill., Fabaceae, along with six known compounds, sitosterol 3-O-β-D-glucopyranoside, 4-methoxygallic acid, syringic acid, quercetin, 6"-O-acetylvitexin, quercetin 3-O-β-D-glucopyranoside. The structures of those compounds and others were determined through spectral analyses. Compounds distemonanthoside, sitosterol 3-O-β-D-glucopyranoside, 4-methoxygallic acid and quercetin were tested against a clinical isolate strain of Mycobacterium tuberculosis AC 45; they exhibited good to moderate antitubercular activities with MIC values ranged from 31.25 to 125 µg/ml.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Idioma: En Revista: Rev. bras. farmacogn Asunto de la revista: FARMACIA Año: 2017 Tipo del documento: Article / Project document País de afiliación: Camerún Pais de publicación: Brasil
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Idioma: En Revista: Rev. bras. farmacogn Asunto de la revista: FARMACIA Año: 2017 Tipo del documento: Article / Project document País de afiliación: Camerún Pais de publicación: Brasil