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Influence of biomaterials on scintigraphic diagnosis of periprosthetic infections. Ceftizoxime-99m technetium model
Teixeira, Luiz Eduardo Moreira; Pádua, Bruno Jannotti; Castilho, André Moreira; Araújo, Ivana Duval de; Andrade, Marco Antônio Percope de; Cardoso, Valbert Nascimento; Diniz, Simone Odília; Leal, Jefferson Soares; Takenaka, Isabella Kuniko.
Afiliación
  • Teixeira, Luiz Eduardo Moreira; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Pádua, Bruno Jannotti; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Castilho, André Moreira; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Araújo, Ivana Duval de; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Andrade, Marco Antônio Percope de; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Cardoso, Valbert Nascimento; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Diniz, Simone Odília; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Leal, Jefferson Soares; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
  • Takenaka, Isabella Kuniko; Universidade Federal de Minas Gerais. Department of Locomotive Apparatus. Belo Horizonte. BR
Acta cir. bras ; Acta cir. bras;33(1): 14-21, Jan. 2018. tab, graf
Article en En | LILACS | ID: biblio-886252
Biblioteca responsable: BR1.1
ABSTRACT
Abstract

Purpose:

To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime.

Methods:

Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3 weeks, scintilographic images were obtained using a gamma chamber. Radioactivity counts were obtained for the region of interest (ROI) on the operated and non-operated paws.

Results:

Groups A, B, and C showed homogenous distribution of the radiopharmaceutical. Hyper uptake was observed in the operated paw from group D. The ROI target count was higher in the two groups with stainless steel implants. Among the control groups, the count was higher in the stainless steel group. Furthermore, among the contaminated groups, the uptake was higher in the stainless steel group, with a significant difference. The target non-target ratio was significantly lower in the control and contaminated groups with both titanium and stainless steel, but the comparison between control groups and contaminated groups was only significant in the former. The cpm/g observed after a decay of 48h showed statistically significant differences between groups.

Conclusion:

Different biomaterials used in implants have an influence on the results of scintigraphy with 99mTc-CFT.
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Acero Inoxidable / Titanio / Ceftizoxima / Compuestos de Organotecnecio / Infecciones Relacionadas con Prótesis / Radiofármacos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Acta cir. bras Asunto de la revista: Cirurgia Geral / Procedimentos Cir£rgicos Operat¢rios Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: LILACS Asunto principal: Acero Inoxidable / Titanio / Ceftizoxima / Compuestos de Organotecnecio / Infecciones Relacionadas con Prótesis / Radiofármacos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Acta cir. bras Asunto de la revista: Cirurgia Geral / Procedimentos Cir£rgicos Operat¢rios Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil