Your browser doesn't support javascript.
loading
CTZ and Calcium Hydroxide Pastes Did Not Cause Hepatic and Renal Alterations in Mice
Lima, Cacilda Castelo Branco; Lima, Marina de Deus Moura; Rizzo, Marcia dos Santos; Oliveira, Caroline Barros; Conde Júnior, Airton Mendes; Moura, Marcoeli Silva de; Moura, Lúcia de Fátima Almeida de Deus.
Afiliación
  • Lima, Cacilda Castelo Branco; Federal University of Piauí. School of Dentistry. Department of Pathology and Dentistry Clinic. Teresina. BR
  • Lima, Marina de Deus Moura; Federal University of Piauí. School of Dentistry. Department of Pathology and Dentistry Clinic. Teresina. BR
  • Rizzo, Marcia dos Santos; Federal University of Piauí. Interdisciplinary Laboratory for Advanced Materials. Teresina. BR
  • Oliveira, Caroline Barros; Federal University of Piaui. Teresina. BR
  • Conde Júnior, Airton Mendes; Federal University of Piauí. Department of Morphology. Teresina. BR
  • Moura, Marcoeli Silva de; Federal University of Piauí. School of Dentistry. Department of Pathology and Dentistry Clinic. Teresina. BR
  • Moura, Lúcia de Fátima Almeida de Deus; Federal University of Piauí. School of Dentistry. Department of Pathology and Dentistry Clinic. Teresina. BR
Pesqui. bras. odontopediatria clín. integr ; 24: e230122, 2024. tab, graf
Article en En | LILACS, BBO | ID: biblio-1564862
Biblioteca responsable: BR1264.1
Ubicación: 1519-0501-pboci-24-e230122.xml
ABSTRACT
ABSTRACT

Objective:

To evaluate the possible renal and hepatic alteration by root canal filling pastes in mice. Material and

Methods:

Fifty-four mice were divided into nine groups and received one polyethylene tube implant containing two filling pastes (CTZ or calcium hydroxide pastes). Empty polyethylene tubes were used as a negative control. All tubes were implanted subcutaneously in the back of the mice. After time intervals of 7, 21, and 63 days, 1.5 mL of blood was collected by cardiac puncture, and serum samples were used for serological testing. Urea, creatinine, aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), and gamma-glutamyltransferase (GGT) were evaluated. Data were analyzed by 2-way ANOVA (p<0.05).

Results:

When comparing CTZ and calcium hydroxide pastes and empty tubes and experimental time intervals, no significant differences in the results were found for any of the biochemical parameters analyzed (p>0.05). No differences were observed in the interactions (material*experimental time intervals) and the biochemical parameters analyzed (p>0.05).

Conclusion:

CTZ and calcium hydroxide pastes did not cause hepatic and renal alterations in mice, demonstrating the pastes' safety.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: BBO / LILACS Asunto principal: Obturación del Conducto Radicular / Hidróxido de Calcio / Tejido Subcutáneo / Antiinfecciosos Límite: Animals Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: ODONTOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
Añadir a Mi BVS
Imprimir
XML
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: BBO / LILACS Asunto principal: Obturación del Conducto Radicular / Hidróxido de Calcio / Tejido Subcutáneo / Antiinfecciosos Límite: Animals Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: ODONTOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil