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Bioabsorbable polymeric Stent for the treatment of Coarctation of the Aorta (CoA) in children: A methodology to evaluate the design and mechanical properties of PLA polymer
Dos Santos, Flávio José; Hernandez, Bruno Agostinho; Santos, Rosana; Machado, Marcel; Souza, Mateus; Capello Sousa, Edson A; Andrade, Aron.
Afiliación
  • Dos Santos, Flávio José; UNESP-São Paulo State University. Bauru. BR
  • Hernandez, Bruno Agostinho; UNESP-São Paulo State University. Bauru. BR
  • Santos, Rosana; PUC-Pontifical Catholic University of São Paulo. São Paulo. BR
  • Machado, Marcel; UNESP-São Paulo State University. Bauru. BR
  • Souza, Mateus; UNESP-São Paulo State University. Bauru. BR
  • Capello Sousa, Edson A; UNESP-São Paulo State University. Bauru. BR
  • Andrade, Aron; Dante Pazzanese Institute of Cardiology. São Paulo. BR
Materials (Basel) ; 16(12): 37374585, jun.2023. ilus
Article en En | CONASS, SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1444422
Biblioteca responsable: BR79.1
ABSTRACT
This study presents a methodology that combines experimental tests and the finite element method, which is able to analyse the influence of the geometry on the mechanical behaviour of stents made of bioabsorbable polymer PLA (PolyLactic Acid) during their expansion in the treatment of coarctation of the aorta (CoA). Tensile tests with standardized specimen samples were conducted to determine the properties of a 3D-printed PLA. A finite element model of a new stent prototype was generated from CAD files. A rigid cylinder simulating the expansion balloon was also created to simulate the stent opening performance. A tensile test with 3D-printed customized stent specimens was performed to validate the FE stent model. Stent performance was evaluated in terms of elastic return, recoil, and stress levels. The 3D-printed PLA presented an elastic modulus of 1.5 GPa and a yield strength of 30.6 MPa, lower than non-3D-printed PLA. It can also be inferred that crimping had little effect on stent circular recoil performance, as the difference between the two scenarios was on average 1.81%. For an expansion of diameters ranging from 12 mm to 15 mm, as the maximum opening diameter increases, the recoil levels decrease, ranging from 10 to 16.75% within the reported range. These results point out the importance of testing the 3D-printed PLA under the conditions of using it to access its material properties; the results also indicate that the crimping process could be disregarded in simulations to obtain fast results with lower computational cost and that new proposed stent geometry made of PLA might be suitable for use in CoA treatments-the approach that has not been applied before. The next steps will be to simulate the opening of an aorta vessel using this geometry.
Asunto(s)

Texto completo: 1 Colección: 06-national / BR Base de datos: CONASS / SES-SP / SESSP-IDPCPROD Asunto principal: Niño Idioma: En Revista: Materials (Basel) Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 06-national / BR Base de datos: CONASS / SES-SP / SESSP-IDPCPROD Asunto principal: Niño Idioma: En Revista: Materials (Basel) Año: 2023 Tipo del documento: Article